An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 351 - 375 of 6333

  1. Foliar application of salicylic acid inhibits the cadmium uptake and accumulation in lettuce (Lactuca sativa L.)

    • Frontiers in Plant Science
    • Introduction

      Salicylic acid (SA) is a multi-functional endogenous phytohormone implicated in the growth, development, and metabolism of many plant species.

      Methods

      This study evaluated the effects of different concentrations of SA (0, 25, 100, 200, and 500 mg/L) on the growth and cadmium (Cd) content of lettuce (Lactuca sativa L.) under Cd stress. The different concentrations of SA treatments were administered through foliar application.

      Results

      • Chemical contaminants
      • Heavy Metals
  2. Analyzing the impacts of cadmium alone and in co-existence with polypropylene microplastics on wheat growth

    • Frontiers in Plant Science
    • Heavy metals typically coexist with microplastics (MPs) in terrestrial ecosystems. Yet, little is known about how the co-existence of heavy metals and MPs affect crops. Therefore, this study aimed to evaluate the impact of cadmium (Cd; 40 mg/L) alone and its co-existence with polypropylene (PP)-MPs (50 and 100 µm) on seed germination, root and shoot growth, seedling dry weight (DW), and antioxidant enzyme activities of wheat.

      • Chemical contaminants
      • Heavy Metals
  3. Determination of 57 pesticide residues in fishery products by GC tandem mass spectrometry combined with QuEChERS (quick, easy, cheap, effective, rugged, and safe) extraction

    • Food Science and Biotechnology
    • An analytical method using GC–MS/MS combined with quick, easy, cheap, effective, rugged, and safe extraction was developed to determine 57 pesticides in fishery products. The limits of detection and quantification (LOD and LOQ, respectively) of the analytical method ranged between 0.91 and 2.12 ng/g wet mass and 3 and 7 ng/g wet mass, respectively. Moreover, the linearity of the calibration curves was acceptable (R2 > 0.99).

      • Chemical contaminants
      • Pesticide residues
  4. Climate and soil pH control the reduction of cadmium in rice during 7 years of biannual liming

    • Plant and Soil
    • Background and aims Liming is widely known as a cost-efficient agricultural practice to reduce cadmium (Cd) concentration in rice (Oryza sativa L.) grain (CdR) in the short term.

      • Chemical contaminants
      • Heavy Metals
  5. Cadmium speciation in cacao beans changes during a fermentation-like incubation

    • Food Chemistry
    • Cadmium (Cd) concentrations in cacao often exceed food limits. Recently, it was shown that cacao bean fermentation enhances Cd solubility, opening potential for Cd mitigation in cacao products. This study was set-up to identify changes in Cd speciation during fermentation.

      • Chemical contaminants
      • Heavy Metals
  6. Phaseolus vulgaris and Pisum sativum, representing ureide and amide legumes respectively, exploit ureides differentially to mitigate the deleterious effects of cadmium toxicity

    • Plant and Soil
    • Purpose Ureides, allantoin and allantoate, are N-rich compounds used for N transport in nodulated ureide legumes. Here, we investigated their role in response of Phaseolus vulgaris and Pisum sativum, representing ureide and amide legumes, respectively, to Cd toxicity. Methods First, ureide content and ureide metabolism in P.

      • Chemical contaminants
      • Heavy Metals
  7. An aptasensor based on the fluorescence resonance energy transfer of nitrogen-doped carbon quantum dots and graphene oxide to detect fipronil in eggs

    • European Food Research and Technology
    • Fipronil, as an excellent insecticide, is widely used around the world, but its residues in agricultural products and the environment cause a series of health and ecological risks. In this study, a novel aptamer sensor for the sensitive, selective, and quantitative detection of fipronil in eggs was prepared using nitrogen-doped carbon quantum dots (NCQDs) modified by fipronil aptamer.

      • Chemical contaminants
      • Pesticide residues
  8. A fast multi-residue analysis of twenty-four classes of pesticide in sesame (Sesamum indicum L.) and their migration into processed products

    • Food Research International
    • Sesame is widely used as a nutritional supplement or condiment because of its nutritious properties and palatable flavor. However, the extensive use of pesticides in sesame fields has paradoxically decreased the nutritional vantage. The current study used QuEChERS with a low-temperature freezing method to develop a multi-residue analytical approach to detect target analytes (pesticides) in sesame seed, sesame oil, sesame paste, and sesame meal.

      • Chemical contaminants
      • Pesticide residues
  9. Alleviation of the Cadmium Toxicity by Application of a Microbial Derived Compound, Ectoine

    • Water, Air, & Soil Pollution
    • Heavy metals are natural components that are formed as a result of biotic activities, accumulate in the ecosystem because they cannot be biodegraded, and thus cause environmental stress.

      • Chemical contaminants
      • Heavy Metals
  10. Zinc and iron enrichment of vermicompost can reduce the arsenic load in rice grain: An investigation through pot and field experiments

    • Journal of Cleaner Production
    • The heavy metalloid arsenic (As), occurring in both trivalent and pentavalent is extremely toxic and has detrimental effect on humans through water-soil-crop transfer. Previously organic and inorganic amendments have been used separately for mitigation of As in rice but there exists a research gap regarding use of them simultaneously.

      • Chemical contaminants
      • Heavy Metals
  11. A CRISPR-Cas9 mutation in sox9b long intergenic noncoding RNA (slincR) affects zebrafish development, behavior, and regeneration

    • Toxicological Sciences
    • The role of long noncoding RNAs (lncRNAs) regulators of toxicological responses to environmental chemicals is gaining prominence. Previously, our laboratory discovered an lncRNA, sox9b long intergenic noncoding RNA (slincR), that is activated by multiple ligands of aryl hydrocarbon receptor (AHR).

      • Chemical contaminants
      • Dioxins
  12. Cattle-related occupational accidents in Japan

    • PLOS ONE
    • by Hilomi Iwai, Hideki Yamamoto Cattle-related injuries are a significant contributing factor in 84.3% of livestock-related incidents in Hokkaido Japan. The specific countermeasures to respond to its characteristics are needed because cattle move freely. This study examined the JA Kyosai mutual aid payment claim form data of the agricultural work-related incidents that occurred from 1st January 2013 to 31st December 2016.

      • Chemical contaminants
      • Heavy Metals
  13. Gene expression analyses reveal potential mechanism of inorganic arsenic‐induced apoptosis in zebrafish

    • Journal of Applied Toxicology
    • Journal of Applied Toxicology, EarlyView. Our previous study showed that sodium arsenite (200 mg/L) affected the nervous system and induced motor neuron development via the Sonic hedgehog pathway in zebrafish larvae. To gain more insight into the effects of arsenite on other signaling pathways, including apoptosis, we have performed quantitative polymerase chain reaction array-based gene expression analyses.

      • Chemical contaminants
      • Heavy Metals
  14. Pb(II)-inducible proviolacein biosynthesis enables a dual-color biosensor toward environmental lead

    • Frontiers in Microbiology
    • With the rapid development of synthetic biology, various whole-cell biosensors have been designed as valuable biological devices for the selective and sensitive detection of toxic heavy metals in environmental water. However, most proposed biosensors are based on fluorescent and bioluminescent signals invisible to the naked eye. The development of visible pigment-based biosensors can address this issue. The pbr operon from Klebsiella pneumoniae is selectively induced by bioavailable Pb(II).

      • Chemical contaminants
      • Heavy Metals
  15. Trophic Transfer, Bioaccumulation, and Detoxification of Lead and Zinc via Sewage Sludge Applied Soil-Barley-Aphid-Ladybird Food Chain

    • Water, Air, & Soil Pollution
    • Assessment of heavy metal (HM) transfer across the food chain has attracted much interest. This study investigated the trophic transfer and toxicokinetics of lead (Pb) and zinc (Zn) in the soil-barley-aphid-ladybird system. At the following rates of 0, 5, 10, 20, and 40% (w/w), sewage sludge from the wastewater treatment plant was applied to the soil.

      • Chemical contaminants
      • Heavy Metals
  16. Combined effects of lead and manganese on locomotor activity and microbiota in zebrafish

    • Ecotoxicology and Environmental Safety
    • Exposure to lead (Pb) and manganese (Mn) during early life influences neurodevelopment and increases the risk of neurodegenerative disorders. However, the level of developmental neurotoxicity due to combined exposure to the two metals remains unclear.

      • Chemical contaminants
      • Heavy Metals
  17. Prediction of the cadmium content in grains of low-accumulating wheat cultivars and soil cadmium threshold for safe production

    • Journal of Cleaner Production
    • Wheat cultivars with low cadmium (Cd) accumulation (WCCA-Cd) are widely used on Cd-contaminated farmland and can effectively reduce the grains Cd content to achieve the clean production in agriculture. However, there is a lack of soil Cd content thresholds specifically for the WCCA-Cd.

      • Chemical contaminants
      • Heavy Metals
  18. Adsorption, Hysteresis, and Trapping of Heavy Metals with Environmental Relevance onto Different Quick Clays and Montmorillonite

    • Water, Air, & Soil Pollution
    • Industrial and pharmaceutical activities are contributing to global environmental contamination. These pollutants having various physicochemical properties are harmful to aquatic organisms and ecosystems. Among daily discharged pollutants, heavy metals can be removed from wastewater by sorption process using natural clay minerals. Quick clays (QCs) are unique glaciomarine clays with unstable structures contributing to their high cation exchange affinity.

      • Chemical contaminants
      • Heavy Metals
  19. Mitigation strategies for excessive cadmium in rice

    • Comprehensive Reviews in Food Science and Food Safety
    • Comprehensive Reviews in Food Science and Food Safety, EarlyView. Cadmium (Cd)-contaminated rice is a human food safety problem that lacks a clear solution. A large amount of rice having an excessive Cd content is processed yearly, but it cannot be discarded and placed in landfills because it will cause secondary pollution. How do we best cope with this toxic rice?

      • Chemical contaminants
      • Heavy Metals
  20. Nutrient Metabolism Pathways Analysis and Key Candidate Genes Identification Corresponding to Cadmium Stress in Buckwheat through Multiomics Analysis

    • Genes
    • Fagopylum tatarium (L.) Gaertn (buckwheat) can be used both as medicine and food and is also an important food crop in barren areas and has great economic value. Exploring the molecular mechanisms of the response to cadmium (Cd) stress can provide the theoretical reference for improving the buckwheat yield and quality.

      • Chemical contaminants
      • Heavy Metals
  21. The TabHLH094–TaMYC8 complex mediates the cadmium response in wheat

    • Molecular Breeding
    • In wheat, TaMYC8 is a negative regulator of cadmium (Cd)-responsive ethylene signaling. In this study, we functionally characterized TabHLH094, a basic helix–loop–helix (bHLH) transcription factor (TF) that inhibits the transcriptional activity of TaMYC8. The TabHLH094 protein was found in the nucleus of tobacco epidermal cells and exhibited transcriptional activation activity.

      • Chemical contaminants
      • Heavy Metals
  22. Cadmium exposure promotes ferroptosis by upregulating Heat Shock Protein 70 in vascular endothelial damage of zebrafish

    • Ecotoxicology and Environmental Safety
    • Cadmium (Cd) exposure is a risk factor for endothelial dysfunction and cardiovascular disease. Ferroptosis is a type of cell death that relies on lipid peroxidation. Whether ferroptosis acts in Cd-induced vascular endothelial damage and the underlying mechanisms remain unclear. Herein, we found that Cd resulted in ferroptosis of vascular endothelial cells (ECs) in vivo and in vitro.

      • Chemical contaminants
      • Heavy Metals
  23. Zinc alleviates cadmium-induced reproductive toxicity via regulating ion homeostasis, metallothionein expression, and inhibiting mitochondria-mediated apoptosis in the freshwater crab Sinopotamon henanense

    • Ecotoxicology and Environmental Safety
    • Cadmium (Cd) is a carcinogenic environmental pollutant that harms male reproductive systems by lowering sperm quality, impairing spermatogenesis, and causing apoptosis. Although zinc (Zn) has been reported to alleviate Cd toxicity, the underlying mechanisms have not been fully elucidated. The aim of this work was to investigate the mitigating effects of Zn on Cd-induced male reproductive toxicity in the freshwater crab Sinopotamon henanense.

      • Chemical contaminants
      • Heavy Metals
  24. Food safety assessment of wines commercialised in the Canary Islands by monitoring of pesticide residues from 2017 to 2019

    • Food Control
    • Population growth, international market expansion, and climate change have caused changes in agricultural practices, including increased use of phytosanitary products to control pests and diseases in food production. The European Union aims to achieve sustainable and high-quality food, with the priority of reducing pesticide use.

      • Chemical contaminants
      • Pesticide residues
  25. Investigation on translocation and accumulation of selected elements in rice grains from soil contaminated with arsenic and cadmium

    • Journal of Food Composition and Analysis
    • With emerging food safety concerns, our study aimed to assess the effect of different levels of soil As and Cd on the accumulation/translocation of toxic (As, Cd) and essential elements (Zn, Fe, Cu, and Mn) by ‘‘red raw samba’’, a hybrid rice variety (short grain; red pericarp; 3.5 months).

      • Chemical contaminants
      • Heavy Metals