An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 451 - 475 of 6333

  1. Cadmium-absorptive Bacillus vietnamensis 151–6 reduces the grain cadmium accumulation in rice (Oryza sativa L.): Potential for cadmium bioremediation

    • Ecotoxicology and Environmental Safety
    • Microbial bioremediation of heavy metal-polluted soil is a promising technique for reducing heavy metal accumulation in crops. In a previous study, we isolated Bacillus vietnamensis strain 151–6 with a high cadmium (Cd) accumulation ability and low Cd resistance. However, the key gene responsible for the Cd absorption and bioremediation potential of this strain remains unclear. In this study, genes related to Cd absorption in B.

      • Chemical contaminants
      • Heavy Metals
  2. Multiresidue Determination of Pesticides in Potato Tuber, Peel, and Pulp by QuEChERS and UHPLC-MS/MS

    • Food Analytical Methods
    • Pesticides have been widely used to control pests and weeds during food production or storage, but when used incorrectly, they can cause damage to human health and the environment. Thus, this study aimed to develop and validate a multiresidue method for the determination of pesticides in potatoes, as well as to evaluate the concentrations in the peel and pulp of the tuber.

      • Chemical contaminants
      • Pesticide residues
  3. Antibiotic Resistance and Food Safety: Perspectives on New Technologies and Molecules for Microbial Control in the Food Industry

    • Antibiotics
    • Antibiotic resistance (ABR) has direct and indirect repercussions on public health and threatens to decrease the therapeutic effect of antibiotic treatments and lead to more infection-related deaths. There are several mechanisms by which ABR can be transferred from one microorganism to another. The risk of transfer is often related to environmental factors.

      • Chemical contaminants
      • Antibiotic residues
  4. Toxic effects of maternal cadmium exposure on the metabolism and transport system of amino acids in the maternal livers

    • Ecotoxicology and Environmental Safety
    • Fetal growth restriction (FGR) is one of the most common obstetric diseases, and affects approximately 10 % of all pregnancies worldwide. Maternal cadmium (Cd) exposure is one of the factors that may increase the risk of the development of FGR. However, its underlying mechanisms remain largely unknown.

      • Chemical contaminants
      • Heavy Metals
  5. Exopolysaccharide-producing bacteria enhanced Pb immobilization and influenced the microbiome composition in rhizosphere soil of pakchoi (Brassica chinensis L.)

    • Frontiers in Microbiology
    • Lead (Pb) contamination of planting soils is increasingly serious, leading to harmful effects on soil microflora and food safety. Exopolysaccharides (EPSs) are carbohydrate polymers produced and secreted by microorganisms, which are efficient biosorbent materials and has been widely used in wastewater treatment to remove heavy metals. However, the effects and underlying mechanism of EPS-producing marine bacteria on soil metal immobilization, plant growth and health remain unclear.

      • Chemical contaminants
      • Heavy Metals
  6. Monitoring arsenic species concentration in rice-based processed products distributed in South Korean markets and related risk assessment

    • Food Science and Biotechnology
    • Rice is an important grain as a major source of carbohydrates in Asia but contains more arsenic (As) than other grains. A total of 239 rice-based processed foods (rice, n = 30; rice cake, n = 30; porridge, n = 39; noodles, n = 33; bread, n = 20; snack, n = 59; powder, n = 28) were purchased in 2019 from domestic markets to measure total As (tAs) and As species.

      • Chemical contaminants
      • Heavy Metals
  7. An integrated remediation approach using combinations of biochar, Rhizobium leguminosarum, and Vigna radiata for immobilizing and dissipating cadmium contaminants from the soil–mustard plant system

    • Frontiers in Plant Science
    • Cadmium (Cd) contamination of soils is an environmental concern, as cadmium harms food crops and can therefore impact human health. The use of combinations of biochar (seeded with Rhizobium leguminosarum) and Vigna radiata (as an intercrop) has the potential to reduce the mobilization of Cd from soil via mustard plants (Brassica juncea). Mustard plants are grown as a food and oil production crop that is consumed worldwide.

      • Chemical contaminants
      • Heavy Metals
  8. Domestic Waste and Wastewaters as Potential Sources of Pharmaceuticals in Nestling White Storks (Ciconia ciconia)

    • Antibiotics
    • Information on the exposure of wild birds to pharmaceuticals from wastewater and urban refuse is scarce despite the enormous amount of drugs consumed and discarded by human populations. We tested for the presence of a battery of antibiotics, NSAIDs, and analgesics in the blood of white stork (Ciconia ciconia) nestlings in the vicinity of urban waste dumps and contaminated rivers in Madrid, central Spain.

      • Chemical contaminants
      • Antibiotic residues
  9. Molecular evidence of widespread benzimidazole drug resistance in Ancylostoma caninum from domestic dogs throughout the USA and discovery of a novel β-tubulin benzimidazole resistance mutation

    • PLOS Pathogens
    • by Abhinaya Venkatesan, Pablo D. Jimenez Castro, Arianna Morosetti, Hannah Horvath, Rebecca Chen, Elizabeth Redman, Kayla Dunn, James Bryant Collins, James S. Fraser, Erik C. Anderson, Ray M. Kaplan, John S. Gilleard Ancylostoma caninum is an important zoonotic gastrointestinal nematode of dogs worldwide and a close relative of human hookworms. We recently reported that racing greyhound dogs in the USA are infected with A.

      • Chemical contaminants
      • Antibiotic residues
  10. Synergistic application of calcium oxide nanoparticles and farmyard manure induces cadmium tolerance in mung bean (Vigna radiata L.) by influencing physiological and biochemical parameters

    • PLOS ONE
    • by Muhammad Waqas Mazhar, Muhammad Ishtiaq, Mehwish Maqbool, Muhammad Ajaib, Iqbal Hussain, Tanveer Hussain, Abida Parveen, Sumaira Thind, Tauqeer Sardar, Raheel Akram, Muhammad Azeem, Alia Gul Mung bean (Vigna radiata L.) grown under heavy metals such as cadmium stress shows poor growth patterns and yield attributes which can be extenuated by the application of calcium and organic manure to the contaminated soil.

      • Chemical contaminants
      • Heavy Metals
  11. Prevalence of Antibiotic Residues in Pork in Kenya and the Potential of Using Gross Pathological Lesions as a Risk-Based Approach to Predict Residues in Meat

    • Antibiotics
    • The human population is growing and urbanising. These factors are driving the demand for animal-sourced proteins. The rising demand is favouring livestock intensification, a process that frequently relies on antibiotics for growth promotion, treatment and prevention of diseases. Antibiotic use in livestock production requires strict adherence to the recommended withdrawal periods.

      • Chemical contaminants
      • Antibiotic residues
  12. Physiological and DNA methylation analysis provides epigenetic insights into kenaf cadmium tolerance heterosis

    • Plant Science
    • Soil heavy metal pollution is one of the most challenging problems. Kenaf is an important natural fiber crop with strong heterosis and a higher tolerance to heavy metals. However, little is known about the molecular mechanisms of kenaf heavy metal tolerance, especially the mechanism of genomic DNA methylation regulating heterosis.

      • Chemical contaminants
      • Heavy Metals
  13. Distribution and accumulation of cadmium in soil under wheat-cultivation system and human health risk assessment in coal mining area of China

    • Ecotoxicology and Environmental Safety
    • The soil contamination caused by the discharge of cadmium (Cd) from coal mining activities has aroused continuous attention due to the detrimental effects on the human health. This study aimed to investigate the characteristics on distribution of Cd in soils and its accumulation in wheat grains under wheat-cultivation system, and further assess the human health risks to adults and children.

      • Chemical contaminants
      • Heavy Metals
  14. Limosilactobacillus fermentum 3872 That Produces Class III Bacteriocin Forms Co-Aggregates with the Antibiotic-Resistant Staphylococcus aureus Strains and Induces Their Lethal Damage

    • Antibiotics
    • LF3872 was isolated from the milk of a healthy lactating and breastfeeding woman. Earlier, the genome of LF3872 was sequenced, and a gene encoding unique bacteriocin was discovered. We have shown here that the LF3872 strain produces a novel thermolabile class III bacteriolysin (BLF3872), exhibiting antimicrobial activity against antibiotic-resistant Staphylococcus aureus strains.

      • Bacterial pathogens
      • Staphylococcus aureus
      • Chemical contaminants
      • Antibiotic residues
  15. Lead acetate induces cartilage defects and bone loss in zebrafish embryos by disrupting the GH/IGF-1 axis

    • Ecotoxicology and Environmental Safety
    • Skeletal system toxicity due to lead exposure has attracted extensive attention in recent years, but few studies focus on the skeletal toxicity of lead in the early life stages of zebrafish. The endocrine system, especially the GH/IGF-1 axis, plays an important role in bone development and bone health of zebrafish in the early life. In the present study, we investigated whether lead acetate (PbAc) affected the GH/IGF-1 axis, thereby causing skeletal toxicity in zebrafish embryos.

      • Chemical contaminants
      • Heavy Metals
  16. Large-Scale Agriculture and Environmental Pollution of Ground and Surface Water and Sediment by Pesticides in the Brazilian Amazon: the Case of the Santarém Region

    • Water, Air, & Soil Pollution
    • The current development model of the agricultural sector in Brazil has considerable potential to cause negative environmental impacts, including the pollution of aquatic ecosystems, as it may contribute to the intensification of erosive processes on deforested soils, to the leaching of eroded materials, and to the consequent siltation of waterbodies with soil particles containing environmental pollutants.

      • Chemical contaminants
      • Pesticide residues
  17. On the contribution of cadmium – citrate complexes to cadmium uptake by durum wheat

    • Plant and Soil
    • Purpose To determine if the increase in Cd uptake by durum wheat in the presence of Cd-citrate is due to dissociation or to the transpiration-driven apoplastic uptake of the complex. Methods A mechanistic model of Cd uptake in hydroponics was developed, formalising the transport of Cd, citrate and their complex, including the dissociation of the latter and its uptake

      • Chemical contaminants
      • Heavy Metals
  18. ABC Transporters and CYP3A4 Mediate Drug Interactions between Enrofloxacin and Salinomycin Leading to Increased Risk of Drug Residues and Resistance

    • Antibiotics
    • Enrofloxacin (ENR) is one of the most common drugs used in poultry production to treat bacterial diseases, and there is a high risk of drug interactions (DDIs) between polyether anticoccidial drugs added to poultry feed over time. This may affect the efficacy of antibiotics or lead to toxicity, posing a potential risk to the environment and food safety. This study aimed to investigate the DDI of ENR and salinomycin (SAL) in broilers and the mechanism of their DDI.

      • Chemical contaminants
      • Antibiotic residues
  19. Geraniol-a potential alternative to antibiotics for bovine mastitis treatment without disturbing the host microbial community or causing drug residues and resistance

    • Frontiers in Cellular and Infection Microbiology
    • Mastitis is one of the most prevalent diseases of dairy cows. Currently, mastitis treatment in dairy cows is mainly based on antibiotics. However, the use of antibiotics causes adverse effects, including drug resistance, drug residues, host-microbiome destruction, and environmental pollution. The present study sought to investigate the potentiality of geraniol as an alternative to antibiotics for bovine mastitis treatment in dairy cows.

      • Bacterial pathogens
      • Staphylococcus aureus
      • Chemical contaminants
      • Antibiotic residues
  20. Comparative transcriptomic analysis reveals the important process in two rice cultivars with differences in cadmium accumulation

    • Ecotoxicology and Environmental Safety
    • To date, Cd remains a major contaminant in rice production. An in-depth exploration of the mechanism that causes genotypic differences in Cd enrichment in rice is necessary to develop strategies to regulate Cd enrichment in rice. Here, two rice cultivars (low grain Cd, ZZ143; and high grain Cd, YX409) displayed different transcriptomic profile patterns when subjected to 100μmol/L Cd stress.

      • Chemical contaminants
      • Heavy Metals
  21. Biodegradation of Microtoxic Phenylpropanoids (Phenylpropanoic Acid and Ibuprofen) by Bacteria and the Relevance for Their Removal from Wastewater Treatment Plants

    • Genes
    • The NSAID ibuprofen (2-(4-isobutylphenyl)propanoic acid) and the structurally related 3-phenylpropanoic acid (3PPA), are widely used pharmaceutical and personal care products (PPCPs) which enter municipal waste streams but whose relatively low rates of elimination by wastewater treatment plants (WWTPs) are leading to the contamination of aquatic resources.

      • Chemical contaminants
      • Dioxins
  22. Wheat Selenium-binding protein TaSBP-A enhances cadmium tolerance by decreasing free Cd2+ and alleviating the oxidative damage and photosynthesis impairment

    • Frontiers in Plant Science
    • Cadmium, one of the toxic heavy metals, robustly impact crop growth and development and food safety. In this study, the mechanisms of wheat (Triticum aestivum L.) selenium-binding protein-A (TaSBP-A) involved in response to Cd stress was fully investigated by overexpression in Arabidopsis and wheat. As a cytoplasm protein, TaSBP-A showed a high expression in plant roots and its expression levels were highly induced by Cd treatment.

      • Chemical contaminants
      • Heavy Metals
  23. Development and application of a rapid screening and quantification method for multi-class herbicide residues in fishery products using UPLC-Q-Tof-MS/MS: Evidence for prometryn residues in shellfish

    • Food Control
    • Quality and safety issues arising from herbicide residues in fishery products are a growing concern. In order to ensure the edible safety of fishery products, a comprehensive assessment of multi-class herbicide residues should be conducted. Hence a modified QuEChERS approach was explored and validated using UPLC-Q-Tof-MS/MS for rapid screening and quantification of 158 herbicide residues in fishery products.

      • Chemical contaminants
      • Pesticide residues
  24. Environmental Factors Influence the Effects of Biochar on the Bioavailability of Cd and Pb in Soil Under Flooding Condition

    • Water, Air, & Soil Pollution
    • Biochar, as a sustainable amendment, effectively remediates soils contaminated with potentially toxic metals. However, the immobilization efficiencies of biochar can vary according to the soil properties.

      • Chemical contaminants
      • Heavy Metals
  25. Edible oil-based switchable-hydrophilicity solvent liquid–liquid microextraction for the determination of lead in food samples using flame-atomic absorption spectrometry

    • Journal of Food Composition and Analysis
    • Edible oil-based switchable-hydrophilicity solvent liquid–liquid microextraction (EO-SHS-LLME) was used prior to the determination of lead as its metal chelate with ammonium pyrrolidine dithiocarbamate (APDC) by flame-atomic absorption spectrometry.

      • Chemical contaminants
      • Heavy Metals