Research Publications (Food Safety)

Keerthana Setlem, Bhairab Mondal, Shylaja Ramlal, Joseph Kingston

Routine dietary consumption of foods that contain aflatoxins is the second leading cause of environmental carcinogenesis worldwide. Aflatoxin-driven mutagenesis is initiated through metabolic activation of aflatoxin B1 (AFB1) to its epoxide form that reacts with N7 guanine in DNA. The resulting AFB1-N7-dG adduct undergoes either spontaneous depurination or imidazole-ring opening...

Monitoring of dairy products should preferably focus on the most relevant food safety hazards in the dairy supply chain. For this purpose, the possible presence of microbiological, chemical, and physical hazards as well as trends in the dairy supply chain that may affect their presence were assessed. A literature review was combined with available data from EFSA, RASFF, and the Dutch monitoring program on chemical hazards as well as expert information.

ABSTRACT

Aflatoxin (AF) is a harmful secondary metabolite that is synthesized by the Aspergillus species. Although AF detection techniques have been developed, techniques for detection of AF synthetic fungi are still required. Techniques such as plate culture methods are continually being modified for this purpose. However, plate culture methods require refinement because they suffer from several issues.

Publication date: December 2016
, Volume 99, Issue 12

Author(s): D. Pantaya, D.P. Morgavi, M. Silberberg, F. Chaucheyras-Durand, C. Martin, Suryahadi, K.G. Wiryawan, H. Boudra

This study was designed to establish if Curcumin (CM) alleviates Aflatoxin B1 (AFB1)-induced hepatotoxic effects and to determine whether alteration of the expression of cytochrome P450 (CYP450) isozymes is involved in the regulation of these effects in chick liver. One-day-old male broilers (n = 120) were divided into four groups and used in a two by two factorial trial in which the main factors included supplementing AFB1 (< 5 vs. 100 μg/kg) and CM (0 vs.

Publication date: Available online 3 November 2016


Author(s): Pranav Chettri, Rosie E. Bradshaw

Publication date: Available online 2 November 2016
Food and Chemical Toxicology

Author(s): Kathy S. Xue, Wenjie Cai, Lili Tang, Jia-Sheng Wang

Publication date: November 2016
, Volume 89, Part 1

Author(s): Arianne Costa Baquião, Evandro Luiz Lopes, Benedito Corrêa

Publication date: March 2017
, Volume 73, Part A

Author(s): Sophia Mavrikou, Evangelia Flampouri, Dimitris Iconomou, Spyridon Kintzios

Piperine is an abundant amide extracted from black pepper seeds which has been shown to have protective effects against cytotoxic and genotoxic carcinogenesis induced by certain chemical carcinogens and aflatoxin B1 (AFB1) in vitro. The aim of this work was to study, in vivo, the antigenotoxic potential of feed-added piperine on broiler chickens experimentally intoxicated with AFB1, using micronucleus and comet assays.

Aflatoxins and melanins are the products of a polyketide biosynthesis. In this study, the search of potential inhibitors of the aflatoxin B1 (AFB1) biosynthesis was performed among compounds blocking the pigmentation in fungi. Four compounds—three natural (thymol, 3-hydroxybenzaldehyde, compactin) and one synthetic (fluconazole)—were examined for their ability to block the pigmentation and AFB1 production in Aspergillus flavus.

Publication date: December 2016
Source:, Volume 63

Author(s): Nicholas Nduti, Amy McMillan, Shannon Seney, Mark Sumarah, Patrisio Njeru, Mercy Mwaniki, G. Reid

Abstract

BACKGROUND

Aflatoxin B1 (AFB1), as a toxic fungal metabolite, can be found in baby foods, which can lead to serious complications for children's health. In this study, 48 commercial baby foods available in the Iranian market were investigated for the presence of AFB1, using a high performance liquid chromatography (HPLC) system equipped with post-column photochemical derivatization and a fluorescence detector.

Publication date: 1 April 2017
, Volume 220

Author(s): Yichen Hu, Jinming Zhang, Weijun Kong, Gang Zhao, Meihua Yang

Publication date: February 2017
, Volume 61

Author(s): Marta H. Taniwaki, Jens C. Frisvad, Larissa S. Ferranti, Aline de Souza Lopes, Thomas O. Larsen, Maria Helena P. Fungaro, Beatriz T. Iamanaka

Publication date: December 2016
, Volume 122

Author(s): Belén Peromingo, Alicia Rodríguez, Victoria Bernáldez, Josué Delgado, Mar Rodríguez

Publication date: Available online 13 October 2016
Food and Chemical Toxicology

Author(s): Bui Thi Mai Huong, Le Danh Tuyen, Do Huu Tuan, Leon Brimer, Anders Dalsgaard

This study investigated the presence of aflatoxin M1 (AfM1) in dairy cows’ milk, given predefined scenarios for milk production, compound feed (CF) contamination with aflatoxin B1 (AfB1), and inclusion rates of ingredients, using Monte Carlo simulation modelling. The model simulated a typical dairy farm in the Netherlands. Six different scenarios were considered, based on two lactation and three CF composition scenarios.

This work presents current information on the presence of aflatoxins (AFs) and zearalenone (ZEN) in feed and feed ingredients from Punjab, Pakistan. The 105 samples tested were concentrated feed, i.e., cotton seed meal (18 samples) and soybean meal (14), and feed ingredients, i.e., crushed corn (17), crushed wheat (15), barley (17). and poultry feed (24). Samples were analyzed using high-performance liquid chromatography equipped with a fluorescence detector.

This study was conducted to investigate the toxic effects of aflatoxin B1 (AFB1) and evaluate the effects of sporoderm-broken spores of Ganoderma lucidum (SSGL) in relieving aflatoxicosis in broilers.

Abstract

Aims

isolate and characterize native yeast strains from broilers' environment as feedstuff, faeces and gut, and to evaluate their binding capacity for aflatoxin B1 (AFB1).