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Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 2051 - 2075 of 41888

  1. Combining Nanopore Sequencing with Recombinase Polymerase Amplification Enables Identification of Dinoflagellates from the Alexandrium Genus, Providing a Rapid, Field Deployable Tool

    • Toxins
    • The armoured dinoflagellate Alexandrium can be found throughout many of the world’s temperate and tropical marine environments. The genus has been studied extensively since approximately half of its members produce a family of potent neurotoxins, collectively called saxitoxin. These compounds represent a significant threat to animal and environmental health. Moreover, the consumption of bivalve molluscs contaminated with saxitoxin poses a threat to human health.

      • Natural toxins
      • Shellfish toxins
  2. Whole-genome sequencing and phylogenetic analysis capture the emergence of a multi-drug resistant Salmonella enterica serovar Infantis clone from diagnostic animal samples in the United States

    • Frontiers in Microbiology
    • Introduction Salmonella enterica is a major cause of foodborne illness in the United States. A multi-drug resistant (MDR) emergent Salmonella Infantis (ESI) with a megaplasmid (pESI) was first identified in Israel and Italy and subsequently reported worldwide.

      • Bacterial pathogens
      • Salmonella
  3. Short-Term Interactions of Noctiluca scintillans with the Toxic Dinoflagellates Dinophysis acuminata and Alexandrium minutum: Growth, Toxins and Allelopathic Effects

    • Toxins
    • The Galician Rías (NW Iberian Peninsula) are an important shellfish aquaculture area periodically affected by toxic episodes often caused by dinoflagellates such as Dinophysis acuminata and Alexandrium minutum, among others. In turn, water discolorations are mostly associated with non-toxic organisms such as the heterotrophic dinoflagellate Noctiluca scintillans, a voracious non-selective predator.

      • Natural toxins
      • Shellfish toxins
  4. The effect of dietary Yucca schidigera extract supplementation on productive performance, egg quality and gut health in laying hens with Clostridium perfringens and coccidia challenge

    • Poultry Science
    • Yucca schidigera extract (YSE) is a green feed additive that is known to reduce toxic gas emissions and promote intestinal health in animal production. This study investigated the potential of dietary YSE supplementation to mitigate the negative effect of Clostridium perfringens and coccidia infection on productive performance and gut health in laying hens.

      • Bacterial pathogens
      • Clostridium perfringens
  5. Controlled Experimental Infection in Pigs with a Strain of Yersinia enterocolitica Harboring Genetic Markers for Human Pathogenicity: Colonization and Stability

    • Infection and Immunity
    • Infection and Immunity, Ahead of Print. Yersinia enterocolitica (Ye) is one of the major causes of foodborne zoonosis. The BT4/O:3 bioserotype is most commonly isolated in human infections. Pigs are considered the main reservoir of Ye, and hence, understanding the dynamics of infection by this pathogen at the individual and group levels is crucial. In the present study, an experimental model was validated in Large White pigs infected with a BT4/O:3 strain.

      • Bacterial pathogens
      • Yersinia
  6. Protective Effect of Willow (Salix babylonica L.) on Fish Resistance to Vibrio parahaemolyticus and Vibrio alginolyticus

    • Antibiotics
    • Vibrio spp. cause vibriosis in many saltwater and freshwater aquatic species, such as fish, crustaceans, and mollusks. Vibrio parahaemolyticus and Vibrio alginolyticus are among the few Vibrio species commonly found in infections in fish. This study aimed at investigating the chemical composition and evaluating the antibacterial activities of Salix babylonica L.

      • Bacterial pathogens
      • Vibrio
  7. Management of acid and alkaline phosphatase, dehydrogenase activities by sugarcane industry waste under lead contamination- A case study of Indian Vertisol

    • PLOS ONE
    • by M. L. Dotaniya, M. C. Nagar, Amita Sharma, C. K. Dotaniya, Rajendiran S., V. B. Singh, R. K. Doutaniya, J. K. Saha Soil fertility management and crop productivity both are inter-related need extensive attention for sustainability. Industries are being built, which over time produces a lot of effluents containing heavy metal(s), which is then dumped on healthy soils and water bodies.

      • Chemical contaminants
      • Heavy Metals
  8. Quantification of Element Levels and Arsenic Species in Commonly Available Rice in Sri Lanka and Assessment of Adverse Health Effects

    • International Journal of Food Science & Technology
    • International Journal of Food Science &Technology, Accepted Article. Quantification of some important elements, including several heavy metals, and assessment of health risks associated with rice consumption was conducted. Twelve different rice varieties were analyzed for fourteen metals i.e. As, Ba, Cd, Co, Cr, Cu, Fe, Mn, Ni, Pb, Se, Sr, U, and Zn using Inductively Coupled Plasma–Mass Spectrometry (ICP-MS).

      • Chemical contaminants
      • Heavy Metals
  9. Deoxynivalenol affects cell metabolism in vivo and inhibits protein synthesis in IPEC-1 cells

    • Mycotoxin Research
    • Deoxynivalenol is present in forage crops in concentrations that endanger animal welfare but is also found in cereal-based food. The amphipathic nature of mycotoxins allows them to cross the cell membrane and interacts with different cell organelles such as mitochondria and ribosomes. In our study, we investigated the gene expression of several genes in vivo and in vitro that are related to the metabolism.

      • Natural toxins
      • Mycotoxins
  10. Inactivation of zearalenone (ZEN) and deoxynivalenol (DON) in complete feed for weaned piglets: Efficacy of ZEN hydrolase ZenA and of sodium metabisulfite (SBS) as feed additives

    • Mycotoxin Research
    • Female pigs respond sensitive both to DON and ZEN with anorexia and endocrine disruption, respectively, when critical diet concentrations are exceeded. Therefore, the frequent co-contamination of feed by DON and ZEN requires their parallel inactivation. The additive ZenA hydrolyzes ZEN while SBS inactivates DON through sulfonation.

      • Natural toxins
      • Mycotoxins
  11. Mechanism of Inhibiting the Growth and Aflatoxin B1 Biosynthesis of Aspergillus flavus by Phenyllactic Acid

    • Toxins
    • Phenyllactic acid (PLA), a promising food preservative, is safe and effective against a broad spectrum of food-borne pathogens. However, its mechanisms against toxigenic fungi are still poorly understood. In this study, we applied physicochemical, morphological, metabolomics, and transcriptomics analyses to investigate the activity and mechanism of PLA inhibition of a typical food-contaminating mold, Aspergillus flavus. The results showed that PLA effectively inhibited the growth of A.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  12. An Edible Biopolymeric Microcapsular Wrapping Integrating Lytic Bacteriophage Particles for Salmonella enterica: Potential for Integration into Poultry Feed

    • Antibiotics
    • This research work aimed at developing an edible biopolymeric microcapsular wrapping (EBMW) integrating lytic bacteriophage particles for Salmonella enterica, with potential application in poultry feed for biocontrol of that pathogen. This pathogen is known as one of the main microorganisms responsible for contamination in the food industry and in foodstuff.

      • Bacterial pathogens
      • Salmonella
  13. Complete Genome Sequence of Campylobacter jejuni BSD5, a Multidrug-Resistant Isolate from a Poultry Processing Facility in the United States

    • Microbiology Resource Announcements
    • Microbiology Resource Announcements, Ahead of Print. Raw poultry can harbor microbial pathogens. Campylobacter jejuni BSD5, isolated from a critical control point within a poultry production plant, was sequenced. Genome annotation revealed several virulence genes including antibiotic resistance genes in agreement with the phenotypic results, indicating a potential risk of this strain to public health.

      • Bacterial pathogens
      • Campylobacter
  14. Inorganic arsenic speciation analysis in food using HPLC/ICP-MS: Method development and validation

    • Journal of Food and Drug Analysis
    • Arsenic (As) compounds can be classified as organic or inorganic, with inorganic arsenic (iAs) having significantly higher toxicity than organic As. As may accumulate in food materials that have been exposed to As-contaminated environments. Thus, the “Sanitation Standard for Contaminants and Toxins in Foods” published by the Ministry of Health and Welfare set the standard limits for iAs content in rice, seaweed, seafood, and marine oils to safeguard public health.

      • Chemical contaminants
      • Heavy Metals
  15. Determination of 24 sulfonamide antibiotics in instant pastries by modified QuEChERS coupled with ultra performance liquid chromatography-tandem mass spectrometry

    • Journal of Food and Drug Analysis
    • There were few reports about antibiotic residues in egg-containing products. In the study, an effective method for the simultaneous determination of 24 sulfonamide antibiotics in two instant pastries based on a modified QuEChERS sample preparation technique coupled with ultra performance liquid chromatography-tandem mass spectrometry was developed.

      • Chemical contaminants
      • Antibiotic residues
  16. Investigation of monacolin K, yellow pigments, and citrinin production capabilities of Monascus purpureus and Monascus ruber (Monascus pilosus)

    • Journal of Food and Drug Analysis
    • Red mold rice (RMR) is a traditional Chinese medicine prepared using Monascus fermentation. M. ruber (pilosus) and M. purpureus have a long history of use as food and medicine. As an economically important starter culture, the relationship between the taxonomy of Monascus and production capabilities of secondary metabolites is crucial for the Monascus food industry.

      • Natural toxins
      • Mycotoxins
  17. Occurrence and associated risk factors of aflatoxin contamination in animal feeds and raw milk from three agroecological zones of Tanzania

    • World Mycotoxin Journal
    • Aflatoxins (AFs) are natural toxic compounds produced by a specific type of fungi, which subsequently contaminate foods and animal feeds, potentially carcinogenic to humans. This study assessed the AFs awareness, prevalence and associated risk factors through a survey of the smallholder dairy farmers (SDFs) and livestock feeds and raw cow milk samples from three agroecological zones in Tanzania.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  18. Lactoferrin Relieves Deoxynivalenol-Induced Oxidative Stress and Inflammatory Response by Modulating the Nrf2/MAPK Pathways in the Liver

    • Journal of Agricultural and Food Chemistry
    • Deoxynivalenol (DON), one of the most common mycotoxins contaminating food and feed, has been shown to induce hepatotoxicity. Lactoferrin (LF) enriched in human milk is a critical functional food component and performs the hepatoprotection function.

      • Natural toxins
      • Mycotoxins
  19. Plant Defensin-Dissimilar Thionin OsThi9 Alleviates Cadmium Toxicity in Rice Plants and Reduces Cadmium Accumulation in Rice Grains

    • Journal of Agricultural and Food Chemistry
    • Thionins are important antibacterial peptides in plants. However, the roles of plant thionins, especially the defensin-dissimilar thionins, in alleviating heavy-metal toxicity and accumulation remain unclear.

      • Chemical contaminants
      • Heavy Metals
  20. Aflatoxin in peanuts and maize: an overview on occurrence, regulations, prevention, and control methods

    • World Mycotoxin Journal
    • Aflatoxins belong to a group of highly carcinogenic mycotoxins, produced mainly by Aspergillus flavus and Aspergillus parasiticus in various agricultural food commodities. It is hard to eliminate them from food and feed due to their high stability. Aflatoxin contamination in food grains, particularly peanut and maize, continues to cause significant health concerns in the population of developing nations. They can be fatal to humans and animals.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  21. Optimum synthesis of Au@Ag nanoparticle as plasma amplifier to detect trace concentration of AFB1 via object-binder-metal SERS method

    • Journal of Food and Drug Analysis
    • The problem of aflatoxin contamination emerged gradually in the field of food safety. Surface-enhanced Raman spectroscopy (SERS) is an ultra-sensitive and non-destructive spectroscopy technology with extensive application prospects in the detection field. In this paper, with the detection of AFB1 as the target, Au@Ag NPs substrate with uniform morphology and strong SERS effect was prepared.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  22. Epigenetic Reprogramming in Host-Parasite Coevolution: The Toxoplasma Paradigm

    • Annual Review of Microbiology
    • Like many intracellular pathogens, the protozoan parasite Toxoplasma gondii has evolved sophisticated mechanisms to promote its transmission and persistence in a variety of hosts by injecting effector proteins that manipulate many processes in the cells it invades. Specifically, the parasite diverts host epigenetic modulators and modifiers from their native functions to rewire host gene expression to counteract the innate immune response and to limit its strength.

      • Parasites
      • Toxoplasma gondii
  23. Validation of the Assurance® GDS for Cronobacter Tq II in Infant Formulas, Infant Cereals, Ingredients, and Environmental Samples Collaborative Study: First Action 2021.08

    • Journal of AOAC INTERNATIONAL
    • Background The Assurance® GDS for Cronobacter Tq II assay is a nucleic acid amplification system for the qualitative detection of Cronobacter. The method uses an upfront concentration of the target organism from the enrichment by immunomagnetic separation (IMS) using the PickPen® device. Objective The Assurance GDS for Cronobacter Tq II method was evaluated for Official Methods of AnalysisSM certification.

      • Bacterial pathogens
      • Cronobacter
  24. Enhanced Automated Online Immunoaffinity Liquid Chromatography–Fluorescence Method for the Determination of Aflatoxin M1 in Dairy Products

    • Journal of AOAC INTERNATIONAL
    • Background Aflatoxin M1 (AFM1) is found in the milk of cows exposed to feed spoiled by Aspergillus fungi species. These fungi may produce the secondary metabolite aflatoxin B1, which is converted in the cow liver by hydroxylation to AFM1 and is then expressed in milk. AFM1 is regulated in milk and other dairy products because it can cause serious health issues, such as liver and kidney cancers, in humans and is an immunosuppressant.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  25. Ivermectin: A Critical Review on Characteristics, Properties, and Analytical Methods

    • Journal of AOAC INTERNATIONAL
    • Background Ivermectin is one of the first, safe, broad-spectrum avermectin class of antiparasitic agent, widely used to control parasitic growth in livestock. Ivermectin being highly lipophilic accumulates in fat tissues, causing its long-term existence in the body. Accordingly, ivermectin residues are observed in various animal products such as milk and meat presenting several health hazards.

      • Chemical contaminants
      • Antibiotic residues