Research Publications (Food Safety)

Aflatoxin is the most common type of mycotoxins in contaminated corn, peanuts and rice, which affects the livestock and ultimately endangers human health.

The purpose of this study was to investigate the role of epigenetic DNA methylation and CYPs expression in AFB1-exposed broiler liver and the protective effect of curcumin. Sixty-four one-day-old AA broilers were randomly divided into four groups, including control group, AFB1 group (1 mg/kg AFB1), curcumin + AFB1 group (1 mg/kg curcumin) and curcumin group (300 mg/kg curcumin).

Aflatoxin B1 (AFB1) is a mycotoxin widely present in animal feed and human food, posing a serious threat to animal and human health. This study was aim to illustrate the mechanism of the protective role of MT against AFB1-induced hepatotoxicity, as well as to explore the feasibility of enhancing the tolerance of poultry to AFB1 by upregulating the expression of hepatic MT.

Aflatoxin B1 (AFB1) is a commonly occurring toxicant in animal and human diets, leading to hazardous effects on health. AFB1 is known to be a hepato-toxicant, and the intestinal barrier may play a crucial role in reversing AFB1-induced liver injury.

Aflatoxin B1 (AFB1) is the most dangerous and abundant mycotoxin, which is toxic to almost all animals, and poultry is more sensitive to AFB1 toxicity. Ingesting AFB1-contaminated feed can cause significant liver damage and brings serious harm to poultry, which greatly restricts the development of the poultry industry. The present research was implemented to explore the intervention effect and its mechanism of taraxasterol on liver damage induced by AFB1 in broiler chickens.

With the growing diversity and complexity of diet, animals and humans are at risk of exposure to aflatoxin B1 (AFB1), which is a well-known contaminant in the food chain that causes various toxicological effects. The intestine acts as the first barrier against external contaminants, but the effect of AFB1 on intestinal barrier has not been determined.

Food and feed are frequently co-contaminated with aflatoxin B1 (AFB1) and zearalenone (ZEN). This study investigated the effects of ZEN on the AFB1–induced liver and mammary gland toxicity in pregnant and lactating rats.

Bioenzymatic degradation of aflatoxin B1 (AFB1) is a safe, efficient and environmentally friendly detoxification technology.

Yellow mealworm (Tenebrio molitor) is a supplementary protein source for food and feed and represents a promising solution to manage grain contaminated with Aflatoxin B1 (AFB1).

Aflatoxin B1 (AFB1), a mycotoxin contaminating food and feed, can trigger liver immune toxicity and threaten the poultry industry. Phillygenin (PHI) is a natural lignan derived primarily from Forsythia suspensa with hepatoprotective pharmacological and medicinal properties.

Laccase, a multicopper oxidase, is well known for its industrial potentials to remove environmental pollutants due to its low substrate specificity to oxidize phenols and thus catalytic versatility.

This study set out to assess the mitigative effects of curcumin on AFB1-induced necroptosis and inflammation in chicken liver. Ninety-six one-day-old AA broiler chickens were separated into four groups, including control group, AFB1 (1 mg/kg) group, curcumin (300 mg/kg) + AFB1 (1 mg/kg) group and curcumin (300 mg/kg) group.

Aflatoxin B1 (AFB1) is an unavoidable environmental pollutant commonly found in feed and foodstuffs. It is the most toxic one of all the aflatoxins, which can cause severe impairment to testicular development and function. Yet, the underlying mechanisms of reproductive toxicity in rams sheep remain inconclusive. The study was designed to explore the effects of AFB1 on sheep testes through rumen-microbiota, oxidative stress and apoptosis.

Author(s): Luxi Lin, Pengfei Fu, Nuoman Chen, Ningyu Gao, Qinqin Cao, Ke Yue, Tingting Xu, Chaodong Zhang, Cai Zhang, Fang Liu, Xuebing Wang, Shucheng Huang

Author(s): Qin-qin Cao, Lu-xi Lin, Ting-ting Xu, Ying Lu, Chao-dong Zhang, Ke Yue, Shu-cheng Huang, Hai-ju Dong, Fu-chun Jian

Author(s): Xinghe Wang, Yang He, Jinlong Tian, Ishfaq Muhammad, Mingchun Liu, Changde Wu, Chang Xu, Xiaohuan Zhang

Author(s): Yeqi Zhao, Tiancheng Wang, Peng Li, Jia Chen, Eugenie Nepovimova, Miao Long, Wenda Wu, Kamil Kuca

Author(s): Mehmet Burak Ates, Mustafa Ortatatli

Author(s): Kuntan Wu, Sifan Jia, Jiacai Zhang, Cong Zhang, Shuai Wang, Shahid Ali Rajput, Lvhui Sun, Desheng Qi

Author(s): Liye Zhu, Chuchu Huang, Xuan Yang, Boyang Zhang, Xiaoyun He, Wentao Xu, Kunlun Huang

Author(s): Juan Chang, Tao Wang, Ping Wang, Qingqiang Yin, Chaoqi Liu, Qun Zhu, Fushan Lu, Tianzeng Gao

Author(s): Somenath Das, Vipin Kumar Singh, Abhishek Kumar Dwivedy, Anand Kumar Chaudhari, Neha Upadhyay, Akanksha Singh, Deepika, Nawal Kishore Dubey

Author(s): M. Kashif Saleemi, Kamran Ashraf, S. Tehseen Gul, M. Noman Naseem, M. Sohail Sajid, Mashkoor Mohsin, Cheng He, Muhammad Zubair, Ahrar Khan

Author(s): M. Kashif Saleemi, Kamran Ashraf, S. Tehseen Gul, M. Noman Naseem, M. Sohail Sajid, Mashkoor Mohsin, Cheng He, Muhammad Zubair, Ahrar Khan