An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 276 - 300 of 440

  1. Toxins, Vol. 11, Pages 138: Two Clostridium perfringens Type E Isolates in France

    • Toxins
    • Toxins, Vol. 11, Pages 138: Two Clostridium perfringens Type E Isolates in France

      Toxins doi: 10.3390/toxins11030138

      Authors:
      Laure Diancourt
      Jean Sautereau
      Alexis Criscuolo
      Michel R. Popoff

      • Clostridium perfringens
      • Bacterial pathogens
  2. Toxigenic and pathogenic potential of enteric bacterial pathogens prevalent in the traditional fermented foods marketed in the Northeast region of India

    • International Journal of Food Microbiology
    • Available online 21 February 2019

      Author(s): Santosh Keisam, Ngangyola Tuikhar, Giasuddin Ahmed, Kumaraswamy Jeyaram

      • Clostridium perfringens
      • Listeria monocytogenes
      • Yersinia
      • Staphylococcus aureus
      • Clostridium botulinum
      • Bacterial pathogens
      • Bacillus cereus
  3. Non-toxigenic strain of Clostridioides difficile Z31 reduces the occurrence of C. difficile infection (CDI) in one-day-old piglets on a commercial pig farm

    • Veterinary Microbiology
    • Available online 20 February 2019

      Author(s): C.A Oliveira Júnior, R.O.S Silva, A.P Lage, F.M Coura, C.P Ramos, A.A. Alfieri, R.M.C Guedes, F.C.F Lobato

      • Clostridium perfringens
      • Bacterial pathogens
  4. Combined effect of high pressure and vinegar addition on the control of Clostridium perfringens and quality in nitrite-free emulsion-type sausage

    • Innovative Food Science & Emerging Technologies
    • Publication date: Available online 8 February 2019

      Innovative Food Science & Emerging Technologies

      Author(s): Sang Hui Lee, Juhui Choe, Dong Jin Shin, Hae In Yong, Yukyung Choi, Yohan Yoon, Cheorun Jo

      • Bacterial pathogens
      • Clostridium perfringens
  5. Effect of grape seed extract on heat resistance of Clostridium perfringens vegetative cells in sous vide processed ground beef

    • Food Research International
    • Available online 7 February 2019

      Author(s): Serap Cosansu, Vijay K. Juneja, Marangeli Osoria, Sudarsan Mukhopadhyay

      • Bacterial pathogens
      • Clostridium perfringens
  6. Impact of Eimeria tenella Coinfection on Campylobacter jejuni Colonization of the Chicken [Fungal and Parasitic Infections]

    • Infection and Immunity
    • Eimeria tenella can cause the disease coccidiosis in chickens. The direct and often detrimental impact of this parasite on chicken health, welfare, and productivity is well recognized; however, less is known about the secondary effects that infection may have on other gut pathogens. Campylobacter jejuni is the leading cause of human bacterial foodborne disease in many countries and has been demonstrated to exert negative effects on poultry welfare and production in some broiler lines.

      • Campylobacter
      • Clostridium perfringens
      • Bacterial pathogens
  7. Feeding Rapidly Alters Microbiome Composition and Gene Transcription in the Clownfish Gut [Microbial Ecology]

    • Applied and Environmental Microbiology
    • Diet is a major determinant of intestinal microbiome composition. While studies have evaluated microbiome responses to diet variation, less is understood about how the act of feeding influences the microbiome, independent of diet type.

      • Clostridium perfringens
      • Bacterial pathogens
  8. Immunization with subunits of a novel pilus produced by virulent Clostridium perfringens strains confers partial protection against necrotic enteritis in chickens

    • Veterinary Microbiology
    • Available online 7 January 2019

      Author(s): D. Lepp, S. Ojha, I. Mehdizadeh Gohari, B. Chakravarty, J.F. Prescott, J. Gong

      • Bacterial pathogens
      • Clostridium perfringens
  9. Toxins, Vol. 11, Pages 1: Multiple Parameters Beyond Lipid Binding Affinity Drive Cytotoxicity of Cholesterol-Dependent Cytolysins

    • Toxins
    • Toxins, Vol. 11, Pages 1: Multiple Parameters Beyond Lipid Binding Affinity Drive Cytotoxicity of Cholesterol-Dependent Cytolysins

      Toxins doi: 10.3390/toxins11010001

      Authors:
      Sucharit Ray
      Roshan Thapa
      Peter A. Keyel

      • Clostridium perfringens
      • Bacterial pathogens
  10. An enhanced green fluorescence protein (EGFP)-based reporter assay for quantitative detection of sporulation in Clostridium perfringens SM101

    • International Journal of Food Microbiology
    • Publication date: 16 February 2019

      , Volume 291

      Author(s): Yuki Wakabayashi, Hirofumi Nariya, Mayo Yasugi, Tomomi Kuwahara, Mahfuzur R. Sarker, Masami Miyake

      • Clostridium perfringens
      • Bacterial pathogens
  11. Clostridium perfringens-mediated necrotic enteritis is not influenced by the pre-existing microbiota but is promoted by large changes in the post-challenge microbiota

    • Veterinary Microbiology
    • Publication date: December 2018

      , Volume 227

      Author(s): Jake A. Lacey, Dragana Stanley, Anthony L. Keyburn, Mark Ford, Honglei Chen, Priscilla Johanesen, Dena Lyras, Robert J. Moore

      • Clostridium perfringens
      • Bacterial pathogens
  12. NanI Sialidase Is an Important Contributor to Clostridium perfringens Type F Strain F4969 Intestinal Colonization in Mice [Bacterial Infections]

    • Infection and Immunity
    • Clostridium perfringens type F (formerly enterotoxigenic C. perfringens type A) strains produce an enterotoxin (CPE) to cause acute cases of food poisoning and chronic nonfoodborne human gastrointestinal diseases (NFD), e.g., antibiotic-associated diarrhea (AAD). NFD strains also produce NanI sialidase, an extracellular enzyme that releases sialic acids from sialyated host macromolecules.

      • Clostridium perfringens
      • Bacterial pathogens
  13. Temporal Effects of High Fishmeal Diet on Gut Microbiota and Immune Response in Clostridium perfringens-Challenged Chickens

    • Frontiers in Microbiology
    • Ting Huang, Biao Gao, Wen-Lu Chen, Rong Xiang, Ming-Gui Yuan, Zhi-Hong Xu, Xin-Yu Peng

      • Clostridium perfringens
      • Bacterial pathogens
  14. Sialic acid facilitates binding and cytotoxic activity of the pore-forming Clostridium perfringens NetF toxin to host cells

    • PLOS ONE
    • Iman Mehdizadeh Gohari, Eric K. Brefo-Mensah, Michael Palmer, Patrick Boerlin, John F. Prescott

      • Clostridium perfringens
      • Bacterial pathogens
  15. Toxins, Vol. 10, Pages 405: Interaction of Clostridium perfringens Iota Toxin and Lipolysis-Stimulated Lipoprotein Receptor (LSR)

    • Toxins
    • Toxins, Vol. 10, Pages 405: Interaction of Clostridium perfringens Iota Toxin and Lipolysis-Stimulated Lipoprotein Receptor (LSR)

      Toxins doi: 10.3390/toxins10100405

      Authors:
      Masahiro Nagahama
      Masaya Takehara
      Keiko Kobayashi

      • Clostridium perfringens
      • Bacterial pathogens
  16. Zinc source influences the gene expression of zinc transporters in jejunum and cecal tonsils during broiler challenge with Eimeria maxima and Clostridium perfringens

    • Poultry Science
    • ABSTRACTThe objective of this experiment was to study the effects of dietary zinc (Zn) source on gene expression of Zn transporters (metallothionein [MT], ZIP 3, 5, 8, 9, 10, 11, 13, and 14, and ZnT 1, 4, 5, 6, 7, 9, and 10) in the jejunum and cecal tonsils of broilers challenged with coccidia or coccidia plus Clostridium perfringens.

      • Clostridium perfringens
      • Bacterial pathogens
  17. Effect of probiotic treatment on the clinical course, intestinal microbiome, and toxigenic Clostridium perfringens in dogs with acute hemorrhagic diarrhea

    • PLOS ONE
    • Anna-Lena Ziese, Jan S. Suchodolski, Katrin Hartmann, Kathrin Busch, Alexandra Anderson, Fatima Sarwar, Natalie Sindern, Stefan Unterer

      Introduction

      The impact of probiotics on dogs with acute hemorrhagic diarrhea syndrome (AHDS) has not been evaluated so far. The study aim was to assess the effect of probiotic treatment on the clinical course, intestinal microbiome, and toxigenic Clostridium perfringens in dogs with AHDS in a prospective, placebo-controlled, blinded trial.

      • Clostridium perfringens
      • Bacterial pathogens
  18. NanR Regulates Sporulation and Enterotoxin Production by Clostridium perfringens Type F Strain F4969 [Molecular Pathogenesis]

    • Infection and Immunity
    • Clostridium perfringens type F strains, which produce C. perfringens enterotoxin (CPE), are a major cause of gastrointestinal infections, including the second most prevalent bacterial foodborne illness and 5 to 10% cases of antibiotic-associated diarrhea. Virulence of type F strains is primarily ascribable to CPE, which is synthesized only during sporulation.

      • Clostridium perfringens
      • Bacterial pathogens
  19. Bactericidal activity of neutral electrolyzed water against Bacillus cereus and Clostridium perfringens in cell suspensions and artificially inoculated onto the surface of selected fresh produce and polypropylene cutting boards

    • Food Control
    • Available online 17 September 2018

      Author(s): Hamzah M. Al-Qadiri, Stephanie Smith, Aleksandra Checinska Sielaff, Byju N. Govindan, Mohamed Ziyaina, Nivin Al-Alami, Barbara Rasco

      • Bacterial pathogens
      • Bacillus cereus
      • Clostridium perfringens
  20. Characterization of intestinal immune response to Clostridium perfringens infection in broiler chickens

    • Poultry Science
    • AbstractNecrotic enteritis toxin B (NetB)-producing Clostridium perfringens (CP) type A is the etiological agent of necrotic enteritis (NE) – an economically significant disease in broiler chickens. Understanding the immune response to CP infection in broiler chickens is becoming important to develop effective vaccines against NE.

      • Clostridium perfringens
      • Bacterial pathogens
  21. Toxins, Vol. 10, Pages 341: Clostridium perfringens Enterotoxin: The Toxin Forms Highly Cation-Selective Channels in Lipid Bilayers

    • Toxins
    • Toxins, Vol. 10, Pages 341: Clostridium perfringens Enterotoxin: The Toxin Forms Highly Cation-Selective Channels in Lipid Bilayers

      Toxins doi: 10.3390/toxins10090341

      Authors:
      Roland Benz
      Michel R. Popoff

      • Clostridium perfringens
      • Bacterial pathogens
  22. Response: Commentary: Probing Genomic Aspects of the Multi-Host Pathogen Clostridium perfringens Reveals Significant Pangenome Diversity, and a Diverse Array of Virulence Factors

    • Frontiers in Microbiology
    • Raymond Kiu, Lindsay J. Hall

      • Clostridium perfringens
      • Bacterial pathogens
  23. A Novel Multiplex PCR-Electronic Microarray Assay for Rapid and Simultaneous Detection of Bovine Respiratory and Enteric Pathogens

    • Journal of Virological Methods
    • Available online 10 August 2018

      Author(s): Niroshan Thanthrige-Don, Oliver Lung, Tara Furukawa-Stoffer, Cody Buchanan, Tomy Joseph, Dale L. Godson, John Gilleard, Trevor Alexander, Aruna Ambagala

      • Clostridium perfringens
      • Cryptosporidium parvum
      • Bacterial pathogens
      • Parasites
  24. Poikilothermic Animals as a Previously Unrecognized Source of Fecal Indicator Bacteria in a Backwater Ecosystem of a Large River [Public and Environmental Health Microbiology]

    • Applied and Environmental Microbiology
    • Quantitative information regarding the presence of Escherichia coli, intestinal enterococci, and Clostridium perfringens in poikilotherms is notably scarce.

      • Clostridium perfringens
      • Bacterial pathogens
  25. Characterization of Clostridium perfringens recovered from broiler chicken affected by necrotic enteritis

    • Poultry Science
    • ABSTRACTNecrotic enteritis (NE) caused by Clostridium perfringens has emerged as an important disease associated with major economic losses in the poultry industry worldwide. The ban and voluntary withdraw of antimicrobial growth promoters used to control NE have resulted in resurgence of NE. Moreover, consumer demand for antibiotic free poultry product has continued to grow.

      • Clostridium perfringens
      • Bacterial pathogens