An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 101 - 125 of 440

  1. Predictive modeling and probabilistic risk assessment of Clostridium perfringens in hamburgers and sandwiches

    • Food Science and Biotechnology
    • This study aimed to develop a mathematical model for the survival of Clostridium perfringens in hamburgers and sandwiches and to evaluate their microbial risk. The primary model was developed in hamburgers using 4 strains of C. perfringens at 5, 10, 15, 25 and 37 °C, and the kinetic parameters of the primary model were fitted well with the Weibull model (R2 ≥ 0.95).

      • Bacterial pathogens
      • Clostridium perfringens
  2. Organic Acids and Nature Identical Compounds Can Increase the Activity of Conventional Antibiotics Against Clostridium Perfringens and Enterococcus Cecorum In Vitro

    • The Journal of Applied Poultry Research
    • SUMMARY In a global context of increased antibiotic resistance, feed additives with enhanced antimicrobial properties are a useful and increasingly needed strategy. Organic acids (OA) and botanical molecules such as nature identical compounds (NIC) have been shown to be effective against bacterial infections based on their antimicrobial activity.

      • Bacterial pathogens
      • Clostridium perfringens
  3. Operational Antecedents Associated with Clostridium perfringens Outbreaks in Retail Food Establishments, United States, 2015–2018

    • Foodborne Pathogens and Disease
    • Clostridium perfringens is a common foodborne pathogen, frequently associated with improper cooking, and cooling or reheating of animal products. The U.S. Food and Drug Administration Food Code outlines proper food preparation practices to prevent foodborne outbreaks; however, retail food establishments continue to have C. perfringens outbreaks.

      • Bacterial pathogens
      • Clostridium perfringens
  4. The Effects of Garlic and Red Chilli Pepper Powder on Physicochemical, Microbiological, and Sensory Properties of Cincalok

    • International Journal of Food Science
    • Cincalok, a traditional fermented shrimp, is prepared by mixing rebon shrimps (Acetes sp) with coarse salt and granulated sugar in a certain ratio. This research was aimed at studying the effect of adding garlic and red chilli pepper powder on the physicochemical, microbiological, and sensory properties of cincalok.

      • Bacterial pathogens
      • Bacillus cereus
      • Clostridium perfringens
      • Staphylococcus aureus
  5. Virulent phage vB_CpeP_HN02 inhibits Clostridium perfringens on the surface of the chicken meat

    • International Journal of Food Microbiology
      • Bacterial pathogens
      • Clostridium perfringens
  6. A simple method for purification of epsilon toxin of Clostridium perfringens type D for serum neutralization assay

    • Journal of Microbiological Methods
      • Bacterial pathogens
      • Clostridium perfringens
  7. A triple-sugar regulated Salmonella vaccine protects against Clostridium perfringens-induced necrotic enteritis in broiler chickens

    • Poultry Science
    • Gram-positive Clostridium perfringens type G, the causative agent of necrotic enteritis (NE), has gained more attention in the poultry industry due to governmental restrictions on the use of growth-promoting antibiotics in poultry feed.

      • Bacterial pathogens
      • Clostridium perfringens
      • Salmonella
  8. Severe gastroenteropathy associated with Clostridium perfringens isolation in starving juvenile sturgeons

    • Journal of Fish Diseases
    • Journal of Fish Diseases, EarlyView.

      • Bacterial pathogens
      • Clostridium perfringens
  9. Severe gastroenteropathy associated with Clostridium perfringens isolation in starving juvenile sturgeons

    • Journal of Fish Diseases
    • Journal of Fish Diseases, EarlyView.

      • Clostridium perfringens
      • Bacterial pathogens
  10. Operational Antecedents Associated with Clostridium perfringens Outbreaks in Retail Food Establishments, United States, 2015–2018

    • Foodborne Pathogens and Disease
      • Clostridium perfringens
      • Bacterial pathogens
  11. Virulent phage vB_CpeP_HN02 inhibits Clostridium perfringens on the surface of the chicken meat

    • International Journal of Food Microbiology
    • Author(s): Yuan Tian, Liting Wu, Rui Lu, Hongduo Bao, Yan Zhou, Maoda Pang, Joseph Brown, Juan Wang, Ran Wang, Hui Zhang

      • Clostridium perfringens
      • Bacterial pathogens
  12. A simple method for purification of epsilon toxin of Clostridium perfringens type D for serum neutralization assay

    • Journal of Microbiological Methods
    • Author(s): Lida Abdolmohammadi Khiav, Anahita Emadi, Azadeh Zahmatkesh

      • Clostridium perfringens
      • Bacterial pathogens
  13. Platelet Endothelial Cell Adhesion Molecule 1 (CD31) Is Essential for Clostridium perfringens Beta-Toxin Mediated Cytotoxicity in Human Endothelial and Monocytic Cells

    • Toxins
    • Beta toxin (CPB) is a small hemolysin beta pore-forming toxin (β-PFT) produced by Clostridium perfringens type C. It plays a central role in the pathogenesis of necro-hemorrhagic enteritis in young animals and humans via targeting intestinal endothelial cells. We recently identified the membrane protein CD31 (PECAM-1) as the receptor for CPB on mouse endothelial cells.

      • Clostridium perfringens
      • Bacterial pathogens
  14. A worldwide systematic review and meta-analysis of bacteria related to antibiotic-associated diarrhea in hospitalized patients

    • PLOS ONE
    • by Hamid Motamedi, Matin Fathollahi, Ramin Abiri, Sepide Kadivarian, Mosayeb Rostamian, Amirhooshang Alvandi

      Introduction

      Antibiotic-associated diarrhea (AAD) is a major hospital problem and a common adverse effect of antibiotic treatment. The aim of this study was to investigate the prevalence of the most important bacteria that cause AAD in hospitalized patients.

      Materials and methods

      • Clostridium perfringens
      • Staphylococcus aureus
      • Bacterial pathogens
  15. Intestinal changes and immune responses during Clostridium perfringens-induced necrotic enteritis in broiler chickens

    • Poultry Science
    • Author(s): Ali Daneshmand, Hassan Kermanshahi, Javid Mohammed, Mohammad Hadi Sekhavati, Ali Javadmanesh, Monireh Ahmadian, Marzieh Alizadeh, Jamshid Razmyar, Raveendra R. Kulkarni

      • Clostridium perfringens
      • Bacterial pathogens
  16. A triple-sugar regulated Salmonella vaccine protects against Clostridium perfringens-induced necrotic enteritis in broiler chickens

    • Poultry Science
    • Author(s): Shifeng Wang, Charles L. Hofacre, Soo-Young Wanda, Jingyu Zhoua Richard A. Callum, Bob Nordgren, Roy Curtiss Gram-positive Clostridium perfringens type G, the causative agent of necrotic enteritis (NE), has gained more attention in the poultry industry due to governmental restrictions on the use of growth-promoting antibiotics in poultry feed.

      • Bacterial pathogens
      • Clostridium perfringens
      • Salmonella
  17. Experimental induction of necrotic enteritis with or without predisposing factors using netB positive Clostridium perfringens strains

    • Gut Pathogens
    • Background

      • Clostridium perfringens
      • Bacterial pathogens
  18. Study of aerobic and anaerobic bacterial profile of nosocomial infections and their antibiotic resistance in a referral center, Southwest Iran: A three year cross-sectional study

    • PLOS ONE
    • by Nazanin Ahmadkhosravi, Azar Dokht Khosravi, Aram Asareh Zadegan Dezfuli, Mohammad Hashemzadeh, Morteza Saki, Fatemeh Jahangiri Mehr, Farokh Izadpour

      Background

      • Clostridium perfringens
      • Staphylococcus aureus
      • Bacterial pathogens
  19. Characterization of Clostridium perfringens bacteriophages and their application in chicken meat and milk

    • International Journal of Food Microbiology
    • Author(s): Tahir Noor Mohammadi, Cunkuan Shen, Yuncheng Li, Mahmoud Gamaleldin Zayda, Jun Sato, Yoshimitsu Masuda, Ken-ichi Honjoh, Takahisa Miyamoto

      • Bacterial pathogens
      • Clostridium perfringens
  20. Effects of Dietary Glucose Oxidase on Growth performance and Intestinal Health of AA Broilers Challenged by Clostridium perfringens

    • Poultry Science
    • Author(s): Yizhu Zhao, Jiahuan Fu, Peng Li, Ningbo Chen, Yanjie Liu, Dan Liu, Yuming Guo

      • Clostridium perfringens
      • Bacterial pathogens
  21. Comparative Study of the Gut Microbiota Among Four Different Marine Mammals in an Aquarium

    • Frontiers in Microbiology
    • Despite an increasing appreciation in the importance of host–microbe interactions in ecological and evolutionary processes, information on the gut microbial communities of some marine mammals is still lacking. Moreover, whether diet, environment, or host phylogeny has the greatest impact on microbial community structure is still unknown.

      • Clostridium perfringens
      • Vibrio
      • Bacterial pathogens
  22. Coinfection of Clostridium perfringens and Escherichia coli in gas-producing perianal abscess diagnosed by 16S rDNA sequencing: a case report

    • Gut Pathogens
    • Background

      • Clostridium perfringens
      • Bacterial pathogens
  23. Cathepsin Release from Lysosomes Promotes Endocytosis of Clostridium perfringens Iota-Toxin

    • Toxins
    • Iota-toxin from Clostridium perfringens type E is a binary toxin composed of two independent proteins: actin-ADP-ribosylating enzyme component, iota-a (Ia), and binding component, iota-b (Ib). Ib binds to target cell receptors and mediates the internalization of Ia into the cytoplasm. Extracellular lysosomal enzyme acid sphingomyelinase (ASMase) was previously shown to facilitate the internalization of iota-toxin.

      • Clostridium perfringens
      • Bacterial pathogens
  24. The Effects of Garlic and Red Chilli Pepper Powder on Physicochemical, Microbiological, and Sensory Properties of Cincalok

    • International Journal of Food Science
    • Cincalok, a traditional fermented shrimp, is prepared by mixing rebon shrimps (Acetes sp) with coarse salt and granulated sugar in a certain ratio. This research was aimed at studying the effect of adding garlic and red chilli pepper powder on the physicochemical, microbiological, and sensory properties of cincalok.

      • Clostridium perfringens
      • Staphylococcus aureus
      • Bacterial pathogens
      • Bacillus cereus
  25. Survival of Clostridium perfringens, Staphylococcus aureus and Salmonella enterica in alternatively cured bacon during cooking and process deviations

    • Meat Science
    • Author(s): Shannon M. Cruzen, Hayriye Cetin-Karaca, Rodrigo Tarté, Joseph G. Sebranek, James S. Dickson Pork bellies were injected with four different alternative curing brines. The bellies were inoculated on the surface and at a depth of 1 cm with multiple strains of Clostridium perfringens, Staphylococcus aureus and Salmonella enterica. The bellies were processed using either a standard process cycle or an interrupted process cycle to simulate a process deviation.

      • Bacterial pathogens
      • Clostridium perfringens
      • Salmonella
      • Staphylococcus aureus