Research Publications (Food Safety)

Lactococcus lactis subsp. cremoris MG1363 is a model for the lactic acid bacteria (LAB) used in the dairy industry. The proteolytic system, consisting of a proteinase, several peptide and amino acid uptake systems, and a host of intracellular peptidases, plays a vital role in nitrogen metabolism and is of eminent importance for flavor formation in dairy products. The dipeptidase PepV functions in the last stages of proteolysis.

To discover natural-product-based pesticides, 7β-oxycarbonylandrographolide derivatives were stereoselectively constructed from a labdane diterpenoid andrographolide.

by Lucille Rey-Cadilhac, Ronan Cariou, Anne Ferlay, Catherine Jondreville, Carole Delavaud, Yannick Faulconnier, Sébastien Alcouffe, Pascal Faure, Philippe Marchand, Bruno Le Bizec, Stefan Jurjanz, Sylvain Lerch Food safety crises involving persistent organic pollutants [POPs, e.g. dioxins, polychlorinated biphenyls (PCBs), organochlorine pesticides] lead to systematic slaughter of livestock to prevent their entry into the food chain.

by Sylvain Lerch, Lucille Rey-Cadilhac, Ronan Cariou, Yannick Faulconnier, Catherine Jondreville, Denis Roux, Gaud Dervilly-Pinel, Bruno Le Bizec, Stefan Jurjanz, Anne Ferlay

Author(s): Kailun Yu, Xiuli Zhang, Xuemei Tan, Mengmeng Ji, Yao Chen, Zhongxiao Wan, Zengli Yu

Author(s): Mengmeng Han, Baoyuan Wang, Guilong Song, Shengqing Shi

Author(s): Yoo-Jin Park, Md Saidur Rahman, Won-Ki Pang, Do-Yeal Ryu, Bongki Kim, Myung-Geol Pang

Inhalation of odors can affect physiological parameter and change gene expression‐related specific function. 2,5‐Dimethyl‐4‐hydroxy‐3(2H)‐furanone (DMHF) is one of the major odor compounds generated by the Maillard reaction. We previously reported that the inhalation of DMHF decreased systolic blood pressure via the autonomic nervous system in rats. The autonomic nervous system is also closely related to appetite regulation.

Amphiphilic diblock copolymers consisting of a hydrophobic core containing a polymerized ionic liquid and an outer shell composed of poly(N‐isoprolylacrylamide) were investigated by CE and asymmetrical flow field flow fractionation. The polymerized ionic liquid comprised poly(2‐(1‐butylimidazolium‐3‐yl)ethyl methacrylate tetrafluoroborate) with a constant block length (n = 24), while the length of the poly(N‐isoprolylacrylamide) block varied (n = 14; 26; 59; 88).

The ATP binding cassette (ABC) transporter LptB2FGC extracts LPS from the inner membrane and powers the transport of the glycolipid to the cell surface in Gram‐negative bacteria. Our study shows that changes to the LPS structure and the transporter can affect how the function of the cytoplasmic LptB ATPase is coupled to the extraction of LPS by LptFG by either promoting or interfering with the collapse of the substrate‐binding cavity.

Objectives. To evaluate how lowering the blood lead level (BLL) intervention threshold affects childhood lead testing policy.

Ever-expanding environmental pollution is causing a rise in cyanobacterial blooms and the accumulation of plastics in water bodies. Consequently, exposure to mixtures of cyanotoxins and plastic-related contaminants such as bisphenols (BPs) is of increasing concern.

Ten new cassane diterpenoids, caesalpulcherrins A–J (1–10), together with 11 known analogues (11–21) were isolated from the aerial parts of Caesalpinia pulcherrima. Their structures and relative stereochemistry were elucidated by spectrometric and spectroscopic methods, including one-dimensional (1D) and two-dimensional (2D) NMR, high-resolution electrospray ionization mass spectrometry (HRESIMS), and single-crystal X-ray diffraction analysis.

Reducing Cd bioavailability in the systemic circulation is an alternative strategy to reduce Cd exposure. The influence of 39 dietary components on Cd bioaccessibility in water or rice was determined using an in vitro gastrointestinal model, following which an in vivo bioassay was used to determine the most effective components on Cd bioavailability in rice. The results showed that several components significantly reduced the solubility of Cd (10–98%) in the intestinal phase.

Author(s): Maria A. Fraser, Lei Chen, Muhammad Ashar, Wei Huang, Jiangning Zeng, Chunfang Zhang, Dongdong Zhang

ABSTRACT In this research, a new ultrasonic‐assisted dispersive micro solid‐phase extraction method based on N‐doped mesoporous carbon sorbent followed by high‐performance liquid chromatography equipped with diode array detector for trace measurement of 1‐hydroxypyrene as a metabolite of exposure to polycyclic aromatic hydrocarbons was optimized. Herein, the hard template method was used for the preparation of N‐doped mesoporous carbon sorbent.

Accumulation, bioavailability and potential ecological risk of seven heavy metals – chromium (Cr), nickel (Ni), copper (Cu), zinc (Zn), arsenic (As), cadmium (Cd) and lead (Pb) – have been analyzed in agricultural soil aggregates with particle size of > 1 mm, 0.25–1 mm, 0.05–0.25 mm, and < 0.05 mm from the Fenhe River Basin (FRB). Accumulation factor (AF) analysis demonstrated that heavy metals tend to be enriched in < 0.05 mm soil aggregate.

Quinolone is a family of widely prescript antibiotics in veterinary medicine. Their excessive use can be causative of quinolone residues in foodstuffs of animal origin. Therefore, a magneto immunofluorescence assay in microwell plate has been developed and validated to screen quinolone in bovine milk. The assay is based on an indirect competitive method where the quinolone in the milk sample competed with the quinolone immobilized on magnetic beads for the anti-quinolone antibody.

Since 2016, the impact of the best available techniques (BAT) on air quality in Bor is significant. Its performance is presented by the air quality assessment with respect to the average annual sulfur dioxide (SO2) emitted concentrations and the total SO2 volume emitted per year from the smelter and sulfuric acid plant, relative to the quantity of processed concentrate in the period when production was conducted with the old technology, in 2013.

Cardoon (Cynara cardunculus L.) is a Mediterranean crop, member of the Asteraceae family, characterized by high production of biomass and secondary metabolites and by a good adaptation to climate change, usable in green chemistry, nutraceutical, and pharmaceutical sectors.

Author(s): Gustav Gbeddy, Ashantha Goonetilleke, Godwin A. Ayoko, Prasanna Egodawatta

Author(s): Wen-Jun Hong, Hongliang Jia, Meng Yang, Yi-Fan Li

Broad application of reduced graphene oxide (rGO) and ubiquitous lead (Pb) pollution may increase the possibility of combined exposure of humans. Information on the combined effects of rGO and Pb in human cells is scarce. This work was designed to explore the potential effects of rGO on Pb‐induced toxicity in human alveolar epithelial (A549) cells. Prepared rGO was polycrystalline in nature.

Author(s): Fei Li, Yuchen Lu, Jingdong Zhang, Yunling Wang, Xiyao Chen, Jingjing Yan, Chaoyang Liu

Author(s): Huaizhan Li, Jianfeng Zha, Hongzhen Zhang, Nanshan Zheng, Guangli Guo