Research Publications from Peer-Reviewed Journals

The Research Publications track research that is published across national and international peer-reviewed journals. The most recent articles are available ahead of print and searchable by Journal Title, Subject, USDA Grant Funding Agencies or FDA Grant Funding Agencies. The research publications are tracked across five subject areas: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, and Viruses.

Wed, 12/01/2021 - 16:00
Colistin and tigecycline are the last options against carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP). Intersecting resistance determinants have been detected between these antibiotics; however, there is only limited evidence of such association. Here, we describe a colistin-resistant CR-hvKP isolated from a patient with severe neonatal bacteremia treated with tigecycline as...
Wed, 12/01/2021 - 12:00
ABSTRACT High Temperature Requirement A (HtrA) was identified as a secreted virulence factor in many pathogenic bacteria, including Listeria monocytogenes. Recently, it was discovered that Helicobacter pylori and Campylobacter jejuni HtrAs can directly cleave the human cell-adhesion molecule E-cadherin, which facilitates bacterial transmigration. HtrAs also interact with extracellular matrix (...
Wed, 12/01/2021 - 12:00
Background Klebsiella pneumoniae is a critically important pathogen in the Philippines. Isolates are commonly resistant to at least 2 classes of antibiotics, yet mechanisms and spread of its resistance are not well studied. Methods A retrospective sequencing survey was performed on carbapenem-, extended spectrum beta-lactam-, and cephalosporin-resistant Klebsiella pneumoniae isolated at 20...
Wed, 12/01/2021 - 12:00
Background Klebsiella species, including the notable pathogen K. pneumoniae, are increasingly associated with antimicrobial resistance (AMR). Genome-based surveillance can inform interventions aimed at controlling AMR. However, its widespread implementation requires tools to streamline bioinformatic analyses and public health reporting. Methods We developed the web application Pathogenwatch,...
Wed, 12/01/2021 - 12:00
Background Klebsiella pneumoniae is a World Health Organization high-priority antibiotic-resistant pathogen. However, little is known about Klebsiella lineages circulating in Nigeria. Methods We performed whole-genome sequencing (WGS) of 141 Klebsiella isolated between 2016 and 2018 from clinical specimens at 3 antimicrobial-resistance (AMR) sentinel surveillance tertiary hospitals in...
Wed, 12/01/2021 - 08:00
by Francesco Saverio Tarantini, Mara Brunati, Anna Taravella, Lucia Carrano, Francesco Parenti, Kar Wai Hong, Paul Williams, Kok Gan Chan, Stephan Heeb, Weng C. Chan As part of a screening programme for antibiotic-producing bacteria, a novel Actinomadura species was discovered from a soil sample collected in Santorini, Greece. Preliminary 16S rRNA gene sequence comparisons highlighted...
Wed, 12/01/2021 - 08:00
by Elif Kaya-Tilki, Miriş Dikmen Chlamydia pneumoniae (Cpn) is a gram-negative intracellular pathogen that causes a variety of pulmonary diseases, and there is growing evidence that it may play a role in Alzheimer’s disease (AD) pathogenesis. Cpn can interact functionally with host histones, altering the host’s epigenetic regulatory system by introducing bacterial products into the host tissue...
Wed, 12/01/2021 - 06:06
Author(s): Haibin Fu, Bingyu Wang, Haihou Wang, Hao Liu, Huifang Xie, Lanfang Han, Ning Wang, Xiaolong Sun, Yanfang Feng, Lihong Xue Conversion of livestock manure to hydrochar through hydrothermal carbonization (HTC) could fix carbon and reduce pollution. The properties of hydrochar largely determined its application; thus, it is significant to comprehensively assess the manure-derived...
Wed, 12/01/2021 - 06:06
Author(s): Weihua Peng, Yingying Liu, Manli Lin, Yan Liu, Cheng Zhu, Linhua Sun, Herong Gui To identify potential toxicity of heavy metals (HMs) in coal fly ash (FA) and coal gangue (CG), this study measured Cd, Cr, Cu, Zn, Pb and Ni in two FAs and two CGs, and assessed their leachates' toxicity to Daphnia magna (D. magna). The results showed that the selected HMs in material and their leachates...
Wed, 12/01/2021 - 06:05
Author(s): Tom Clune, Amy Lockwood, Serina Hancock, Andrew N. Thompson, Sue Beetson, Mieghan Bruce, Angus J. Campbell, Elsa Glanville, Daniel Brookes, Colin Trengove, Ryan O’Handley, Caroline Jacobson The role of infectious diseases including coxiellosis in causing poorer reproductive performance of primiparous ewes are not well studied. The aims of this study were to determine if natural...
Wed, 12/01/2021 - 06:05
Author(s): Sana Ullah, Zhongqiu Li, Said Hassan, Shahid Ahmad, Xinle Guo, Kunyuan Wanghe, Ghulam Nabi The construction of hydropower projects discharges effluents to aquatic bodies. The effluents consist of different chemicals including heavy metals. The current study assessed the effects of effluents discharged from an under-construction hydropower project on the bioaccumulation of heavy metals...
Wed, 12/01/2021 - 06:04
LWT
Author(s): Khashayar Shahin, Hongduo Bao, Shujiao Zhu, Abbas Soleimani-Delfan, Tao He, Mojtaba Mansoorianfar, Ran Wang Phages are strong antibacterial agents commonly used in the food industry, especially phage cocktails that cause much stronger and more stable effects. This study aimed to identify and characterize three absolutely lytic phages of E. coli isolated from poultry farms. Phages O18-...
Wed, 12/01/2021 - 02:01
Ringer tablet-based micelle-mediated extraction-solvent back extraction method coupled to HPLC has been investigated for the determination of neonicotinoid pesticides in honey, cucumber, and orange samples. The method employs the entrapment of the analytes in the micelles of non-ionic surfactant (Triton X-114). By ultrasonication, the ringer tablet is dissolved, and the extractant is released...
Wed, 12/01/2021 - 02:01
Abstract Cadmium (Cd) pollution has become a global environmental issue because Cd gets easily accumulated and translocated in the food chain, threatening human health. Considering the detrimental effects and non-biodegradability of environmental Cd, this is an urgent issue that needs to be addressed through the development of robust, cost-effective, and eco-friendly green routes for monitoring...
Wed, 12/01/2021 - 00:00
Difenoconazole (DIF) and dimethomorph (DIM) are widely used pesticides frequently detected together in environmental samples, so the deleterious effects of combined exposure warrant detailed examination. In this study, the individual and combined effects of DIM and DIF on conventional developmental parameters (hatching rate, deformity rate, lethality) and gene expression were measured in...
Wed, 12/01/2021 - 00:00
Fungal contamination of food, especially by mycotoxigenic fungi, not only reduces the quality of the food, but can also cause serious diseases, thus posing a major food safety challenge to humans. Apart from sound food control systems, there is also a continual need to explore antifungal agents that can inhibit fungal growth and mycotoxin production in food. Many types of fatty acids (FAs) and...
Tue, 11/30/2021 - 22:05
Journal of Food Safety, EarlyView. The aim of the present study was to investigate the antimicrobial mechanism of oregano essential oil (OEO) against Shewanella putrefaciens. Antimicrobial activity of OEO against Shewanella putrefaciens was investigated by the agar disc diffusion method. The change of growth curve, electric conductivity, the integrity of cell membrane, alkaline phosphatase (AKP...
Tue, 11/30/2021 - 16:00
Urbanization causes alteration in atmospheric, soil, and hydrological factors and substantially affects a range of morphological and physiological plant traits. Correspondingly, plants might adopt different strategies to adapt to urbanization promotion or pressure. Understanding of plant traits responding to urbanization will reveal the capacity of plant adaptation and optimize the choice of...
Tue, 11/30/2021 - 16:00
Staphylococcus aureus (S. aureus) is now regarded as a zoonotic agent. Methicillin-susceptible S. aureus (MSSA) ST398 is a livestock-associated bacterium that is most prevalent in China, but there are currently no data available for Shandong. Therefore, the aim of this study was to investigate the epidemiology and characterization of MSSA ST398 from retail pork and bulk tank milk (BTM) in...
Tue, 11/30/2021 - 16:00
The widespread use of commercial polymers composed of a mixture of polylactic acid and polyethene terephthalate (PLA-PET) in bottles and other packaging materials has caused a massive environmental crisis. The valorization of these contaminants via cost-effective technologies is urgently needed to achieve a circular economy. The enzymatic hydrolysis of PLA-PET contaminants plays a vital role in...
Tue, 11/30/2021 - 16:00
Many recent pandemics have been recognized as zoonotic viral diseases. While their origins remain frequently unknown, environmental contamination may play an important role in emergence. Thus, being able to describe the viral diversity in environmental samples contributes to understand the key issues in zoonotic transmission. This work describes the use of a metagenomic approach to assess the...
Tue, 11/30/2021 - 16:00
Finafloxacin is a novel fluoroquinolone with optimal antibacterial activity in low pH environments, therefore offering a therapeutic advantage over some traditional antibiotics, in treating bacterial infections associated with acidic foci. Coxiella burnetii, the causative agent of Q fever, is a bacterium which resides and replicates in acidic intracellular parasitic vacuoles. The efficacy of...
Tue, 11/30/2021 - 14:05
Avian influenza virus (AIV) subtypes H5N1 and H9N2 co-circulate in poultry in Bangladesh, causing significant bird morbidity and mortality. Despite their importance to the poultry value chain, the role of farms in spreading and maintaining AIV infections remains poorly understood in most disease-endemic settings. To address this crucial gap, we conducted a cross-sectional study between 2017 and...
Tue, 11/30/2021 - 08:02
by Bjørn Arne Rukke, Morten Hage, Anders Aak The long-tailed silverfish Ctenolepisma longicaudatum (Lepismatidae: Zygentoma) is a nuisance problem in buildings and a major concern in museums, libraries and archives where it cause damage to historical and priceless items. We used laboratory bioassays and two field studies of infested buildings to evaluate spatial and temporal elements of a...
Tue, 11/30/2021 - 08:02
by Wissal Jame, Bilgen Basgut, Abdikarim Abdi Objective To compare between current evidence of novel glycopeptides against vancomycin for the treatment of gram-positive bacterial infections. Methodology A systematic review and meta-analysis was done. Major databases were searched for eligible randomized control trials that assessed clinical success, microbiological success and safety profile of...
Tue, 11/30/2021 - 08:02
by Clifton K. Fagerquist, Claire E. Dodd Fourteen proteins produced by three pathogenic Escherichia coli strains were identified using antibiotic induction, MALDI-TOF-TOF tandem mass spectrometry (MS/MS) and top-down proteomic analysis using software developed in-house. Host proteins as well as plasmid proteins were identified. Mature, intact protein ions were fragmented by post-source decay (PSD...
Tue, 11/30/2021 - 06:09
Author(s): Minto Michael, Jennifer C. Acuff, Daniel Vega, Amninder S. Sekhon, Lakshmikantha H. Channaiah, Randall K. Phebus Foodborne pathogens like Salmonella and Escherichia coli O121 can endure the harsh low water activity (aw) environment of wheat flour for elongated periods of time and can proliferate when hydrated for baking or other purposes. This study determined the survivability and...
Tue, 11/30/2021 - 00:00
The onset of bloody stools in neonates often results in antibiotic treatment for suspected necrotizing enterocolitis (NEC). Food protein-induced allergic proctocolitis (FPIAP) is an often-neglected differential diagnosis. We performed a retrospective analysis of antibiotic exposure at our tertiary center from 2011 to 2020 that included three time periods of differing antimicrobial stewardship...
Mon, 11/29/2021 - 16:00
As the market indicates a growing interest in organically grown fruit, there is a need for biostimulants to counter the adverse effects of pathogenic fungi and fungal-like-pathogens. Four microbial pathogens (Botrytis cinerea, Verticillium sp., Phytophthora sp., and Colletotrichum sp.) which are the most often causes of strawberry diseases were selected. Five kinds of biostimulants (C1, C2, C3,...
Mon, 11/29/2021 - 16:00
Understanding microbial community dynamics in the alpine cryosphere is an important step toward assessing climate change impacts on these fragile ecosystems and meltwater-fed environments downstream. In this study, we analyzed microbial community composition, variation in community alpha and beta diversity, and the number of prokaryotic cells and virus-like particles (VLP) in seasonal snowpack...
Mon, 11/29/2021 - 16:00
Microbes are the biggest shareholder for the quantitative and qualitative deterioration of food commodities at different stages of production, transportation, and storage, along with the secretion of toxic secondary metabolites. Indiscriminate application of synthetic preservatives may develop resistance in microbial strains and associated complications in human health with broad-spectrum...
Mon, 11/29/2021 - 16:00
Aeromonas are Gram-negative rods widely distributed in the environment. They can cause severe infections in fish related to financial losses in the fish industry, and are considered opportunistic pathogens of humans causing infections ranging from diarrhea to septicemia. The objective of this study was to determine in silico the contribution of genomic islands to A. hydrophila. The complete...
Mon, 11/29/2021 - 16:00
The extent of susceptibility towards miltefosine (Mil), amphotericin B (AmpB), and paromomycin (Paro) was measured among 19 clinical isolates of Leishmania donovani (LD). Thirteen of these clinical isolates were reported to exhibit low susceptibility towards sodium stibogluconate (SSG-R), while six of them were highly susceptible (SSG-S). The degree of clearance of amastigotes (EC50) for these...
Mon, 11/29/2021 - 12:00
Methylmercury (MeHg) is a developmental toxicant capable of eliciting neurocognitive and neuromuscular deficits in children with in utero exposure. Previous research in Drosophila melanogaster uncovered that developmental MeHg exposure simultaneously targets the developing musculature and innervating motor neuron in the embryo, along with identifying Drosophila neuroligin 1 (nlg1) as a gene...
Mon, 11/29/2021 - 12:00
Screening for drug discovery targeting the central nervous system requires the establishment of efficient and highly accurate toxicity test methods that can reduce costs and time while maintaining high throughput using the function of an in vitro neural network. In particular, an evaluation system using a human-derived neural network is desirable in terms of species difference. Despite the...
Mon, 11/29/2021 - 06:05
Author(s): Mohsen Jalali, Amir Meyari Due to the utilization of municipal and industrial wastewater, as well as the uncontrolled use of chemical and livestock fertilizers leafy vegetables have a high content of heavy metals (HMs). Soils and eight vegetable samples extensively used in Iran were collected from numerous vegetable farms to investigate the risk of HMs pollution and human health risk...
Mon, 11/29/2021 - 02:01
The scope of this work was to study the efficacy of the combination of sonication at 35 or 130 kHz with three temperature treatments: 20, 50 and 55 ºC, on the population of artificially inoculated Listeria innocua in strawberries, and on their overall quality. Prior in vitro results showed that temperature was the main factor in decreasing L. innocua population: a maximum of 3.8 log reductions...
Mon, 11/29/2021 - 02:01
Benzophenone-1 (BP1) has been classified as a potential endocrine disruptor due to its reported negative effect on different living beings. In addition, its presence in different water bodies has been detected. In this way, the ultrasonic removal of BP1 was studied considering the effects of the frequency, the power density, and the pollutant initial concentration. In general, results indicated...
Mon, 11/29/2021 - 00:00
The intensifying world-wide spread of mycotoxigenic fungal species has increased the possibility of mycotoxin contamination in animal feed and the human food chain. Growing evidence shows the deleterious toxicological effects of mycotoxins from infants to adults, while large population-based screening programs are often missing to identify affected individuals. The kidney functions as the major...
Mon, 11/29/2021 - 00:00
An increase in human and veterinary fluoroquinolone-resistant Escherichia coli is a global concern. In this study, we isolated fluoroquinolone-resistant E. coli isolates from companion animals and characterized them using molecular epidemiological analysis, multiplex polymerase chain reaction to detect E. coli ST131 and CTX-M type extended-spectrum β-lactamases (ESBL), and multi-locus...
Sun, 11/28/2021 - 22:07
Journal of Applied Microbiology, Accepted Article. Aims The adsorption of lead ions from aqueous solution by macroporous Ca-alginate-lignin (MCAL) beads immobilized with Clostridium tyrobutyricum (C. tyrobutyricum) and free strains was evaluated. Methods and Results The effects of different factors including pH, adsorption time, adsorbent dosage and initial concentration of lead ions were...
Sun, 11/28/2021 - 06:06
Author(s): Apurva Kakade, El-Sayed Salama, Muhammad Usman, Muhammad Arif, Pengya Feng, Xiangkai Li Heavy metals (HMs) contaminated fish is a threat to humans when consumed. Dietary probiotics have evolved as a successful HMs removal approach. In this study, probiotics Enterococcus (EC) sp. and Lactococcus (LC) sp. were evaluated for toxicity alleviation and gut microbiota maintenance in Cyprinus...
Sun, 11/28/2021 - 06:06
Author(s): Muhammad Saqib Rashid, Guijian Liu, Balal Yousaf, Yu Song, Rafay Ahmed, Abdul Rehman, Muhammad Arif, Samina Irshad, Ayesha Imtiyaz Cheema The present study investigated the effectiveness of rice husk biochar (RHB) and chicken manure compost (CMC) amendments (T1: Control, T2: 2% RHB, T3: 2% CMC, T4: 1% RHB + 1% CMC) on the potential mobility of heavy metals (HMs) and the growth of maize...
Sun, 11/28/2021 - 06:06
Author(s): Kamran Banan, Dara Hatamabadi, Hanif Afsharara, Bahar Mostafiz, Hadise Sadeghi, Soheil Rashidi, Amirreza Dowlati Beirami, Mohammad-Ali Shahbazi, Rüstem Keçili, Chaudhery Mustansar Hussain, Fatemeh Ghorbani-Bidkorbeh Misusing or overusing antibiotics in livestock and poultry can result in the accumulation of mentioned drugs in the animal meat. Consequently, its consumption by humans and...
Sun, 11/28/2021 - 06:05
Author(s): Badrul Hisyam Zainudin, Muhammad Isfaiz Iskandar, Suzannah Sharif, Aznie Aida Ahmad, Muhd Fauzi Safian This article discussed a development, optimization, and validation of modified QuEChERS method with liquid chromatography quadrupole time-of-flight mass spectrometry (LC-QTOF-MS) operated in time-of-flight multiple-reaction-monitoring (TOF-MRM) mode for the analysis of ochratoxin A...
Sun, 11/28/2021 - 06:05
Author(s): Zeynal Topalcengiz, Michelle D. Danyluk The purpose of this study was to evaluate the fate of generic Escherichia coli in fecal pats under different field conditions and to predict Salmonella and Shiga toxin-producing E. coli (STEC) survival dynamics based on developed models. Eight trials were conducted during spring and fall in both North and Central Florida. Fresh cattle feces (1g)...
Sun, 11/28/2021 - 06:04
Author(s): Ting Cui, Wenjuan Jiang, Fan Yang, Junrong Luo, Ruiming Hu, Huabin Cao, Guoliang Hu, Caiying Zhang Growing evidences reveal that Nrf2-mediated antioxidant defense response and mitophagy are involved in the toxic mechanism of heavy metals, but the effects of molybdenum (Mo) and cadmium (Cd) co-exposure on Nrf2-mediated antioxidant defense response and mitophagy in duck hypothalamus have...
Sun, 11/28/2021 - 06:04
LWT
Author(s): Deyin Zhao, Qian Wang, Fengxia Lu, Xiaomei Bie, Haizhen Zhao, Zhaoxin Lu, Yingjian Lu Increasing cases of infections by S. aureus in food resulted in a great demand to utilize natural, safe, and effective antimicrobial agents which could inactivate foodborne pathogens in the food industry. A novel class IId bacteriocin, plantaricin 827, produced by Lactobacillus plantarum 163 was...
Sun, 11/28/2021 - 04:01
Dicamba is an important herbicide for controlling post-emergent resistant weeds in soybean farming. Recently, the scientific community and general public have further examined off-target transport mechanisms (e.g., spray drift, volatilization, and tank contamination) and the visual responses of soybeans to ultralow dicamba concentrations. This paper synthesizes key chemical concepts and...
Sun, 11/28/2021 - 00:00
While monitoring the presence of antibiotic resistance in municipal wastewater bacteria from Mexico City, five Escherichia coli isolates were found to be resistant to carbapenems, antibiotics of “last resort” used mostly in hospitals. Further analysis revealed that these carbapenem-resistant isolates carried the gene encoding a metallo-beta-lactamase, NDM-5. The gene was found to be beared by a...

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