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Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 51 - 75 of 893

  1. Metabolome analysis reveals the toxic effects of cadmium exposure on the egg sac of spider Pardosa pseudoannulata

    • Ecotoxicology and Environmental Safety
    • The investigation of the toxic effects of cadmium (Cd) on rice field invertebrates has attracted accumulating attention. Spider grants a novel insight into the impacts of Cd stress on invertebrates, but the effects of Cd-induced toxicity and molecular response mechanism of related metabolites in spider's egg sacs remain elusive.

      • Chemical contaminants
      • Heavy Metals
  2. 24-epibrassinolide improves cadmium tolerance and lateral root growth associated with regulating endogenous auxin and ethylene in Kentucky bluegrass

    • Ecotoxicology and Environmental Safety
    • The application of phytohormones is a viable technique to increase the efficiency of phytoremediation in heavy metal-contaminated soils. The objective of this study was to determine how the application of 24-epibrassinolide (EBR), a brassinosteroid analog, could regulate root growth and tolerance to cadmium (Cd) stress in Kentucky bluegrass.

      • Chemical contaminants
      • Heavy Metals
  3. Effects of chronic exposure to cadmium and copper on the proteome profile of hemolymph in false widow spider Steatoda grossa (Theridiidae)

    • Ecotoxicology and Environmental Safety
    • The aim of this study was to evaluate the quantitative and qualitative changes in the proteome of the hemolymph of female Steatoda grossa spiders (Theridiidae) that were chronically exposed to cadmium and copper in food and were additionally immunostimulated (phorbol 12–myristate 13–acetate (PMA); bacterial suspensions: Staphylococcus aureus (G+), Pseudomonas fluorescens (G–).

      • Chemical contaminants
      • Heavy Metals
  4. Rhizosphere bacteria regulated arsenic bioavailability and accumulation in the soil–Chinese cabbage system

    • Ecotoxicology and Environmental Safety
    • The accumulation of arsenic (As) in Chinese cabbage (Brassica rapa ssp. pekinensis) has recently been a source of concern for a potential risk to human health. It is unknown whether natural variations of As accumulation in different genotypes of Chinese cabbage are related to rhizobacterial characteristics.

      • Chemical contaminants
      • Heavy Metals
  5. Cadmium distribution and transformation in leaf cells involved in detoxification and tolerance in barley

    • Ecotoxicology and Environmental Safety
    • Barley is a diagnostic plant that often used in the research of soil pollution by heavy metals, our research explored the detoxification and tolerance mechanism of cadmium(Cd) in barley through pot experiment.

      • Chemical contaminants
      • Heavy Metals
  6. Polychlorinated dibenzo-p-dioxins/dibenzofurans and mercury in vegetable of the contaminated Ya-Er Lake area: Concentrations, sources, and health risk

    • Ecotoxicology and Environmental Safety
    • The Ya-Er Lake is a seriously polychlorinated dibenzo-p-dioxins/dibenzo-furans (PCDD/Fs) and mercury (Hg)-contaminated lake by pesticide and chlor-alkali plants in China. The oxidation pond method has been conducted to control pollution, moreover, the contaminated sediment was dredged and stacked, becoming a sediment stack yard for vegetable cultivation.

      • Chemical contaminants
      • Dioxins
  7. Deciphering soil amendments and actinomycetes for remediation of cadmium (Cd) contaminated farmland

    • Ecotoxicology and Environmental Safety
    • Soil heavy metal pollution is one of the most serious environmental problems in China, especially cadmium (Cd), which has the most extensive contaminated soil coverage. Therefore, more economical and efficient remediation methods and measures are needed to control soil Cd contamination. In this study, different amendments (biochar (B), organic fertilizer (F), lime (L)) and actinomycetes (A) inoculants were applied to Cd contaminated farmland to explore their effects on wheat growth.

      • Chemical contaminants
      • Heavy Metals
  8. Silicon modification improves biochar’s ability to mitigate cadmium toxicity in tomato by enhancing root colonization of plant-beneficial bacteria

    • Ecotoxicology and Environmental Safety
    • Modification of biochar, such as impregnation with minerals, can improve biochar’s efficacy to mitigate heavy metal toxicity in plants. Biochar amendments can alter plant rhizosphere microbiome, which has profound effects on plant growth and fitness. Here, we tested whether rhizosphere microbiome is involved in the ability of silicon (Si)-modified biochar to mitigate cadmium toxicity in tomato (Solanum lycopersicum L.).

      • Chemical contaminants
      • Heavy Metals
  9. Cultivar-specific response of rhizosphere bacterial community to uptake of cadmium and mineral elements in rice (Oryza sativa L.)

    • Ecotoxicology and Environmental Safety
    • Toxic metal-contaminated farmland from Cadmium (Cd) can enhance the accumulation of Cd and impair the absorption of mineral elements in brown rice. Although several studies have been conducted on Cd exposure on rice, little has been reported on the relationship between Cd and mineral elements in brown rice and the regulatory mechanism of rhizosphere microorganisms during element uptake.

      • Chemical contaminants
      • Heavy Metals
  10. Ameliorative effects of dietary selenium against cadmium toxicity on production performance and egg quality in laying hens

    • Ecotoxicology and Environmental Safety
    • In order to reveal the influences of supplemented dietary selenium (Se) on the suppressive effect of cadmium (Cd) toxicity on performance and egg properties of laying hens, the effects of co-treatment Se and Cd on the performance, egg quality, levels of amino acids and the antioxidant capacity of egg and serum were investigated.

      • Chemical contaminants
      • Heavy Metals
  11. Persistence of Salmonella Typhimurium and antibiotic resistance genes in different types of soil influenced by flooding and soil properties

    • Ecotoxicology and Environmental Safety
    • Salmonella is a zoonotic foodborne bacterial pathogen that can seriously harm health. Persistence of Salmonella and antibiotic resistance genes (ARGs) in different types of soil under flooding and natural conditions are rare explored. This study investigated the dynamic changes of the Salmonella, ARGs and bacterial communities in three types of soils applied with pig manure in lab scale.

      • Bacterial pathogens
      • Salmonella
  12. Amelioration of cholesterol sulfate for lead-induced CTX cell apoptosis based on BDNF signaling pathway mediated cholesterol metabolism

    • Ecotoxicology and Environmental Safety
    • Lead (Pb), as a deleterious heavy metal, ubiquitously exists in environment and industry, which engenders multi-organ disfunction, especially the brain of infants who are vulnerable to attack from lead-induced neurotoxicity. Although cholesterol sulfate (CS) is crucial constituent of cell membranes and precursor of neurosteroids, which maintains the function and survival of neurons, the role of CS in lead-induced neurological damage still remains incomplete.

      • Chemical contaminants
      • Heavy Metals
  13. Effects of malic acid and EDTA on oxidative stress and antioxidant enzymes of okra (Abelmoschus esculentus L.) exposed to cadmium stress

    • Ecotoxicology and Environmental Safety
    • Environmental stresses, including heavy metal pollution, are increasing at a growing rate and influencing arable lands. Chelators play an essential role in several biochemical pathways in the cells of plants treated with heavy metals. This research evaluated the modifying effect of malic acid (MA) and ethylenediaminetetraacetic acid (EDTA) on the physiological and biochemical parameters of okra plants exposed to Cd stress in which the okra plants were cultivated in hydroponic conditions.

      • Chemical contaminants
      • Heavy Metals
  14. Different responses to joint exposure to cadmium and zinc depends on the sex in Populus cathayana

    • Ecotoxicology and Environmental Safety
    • The alarming increase in soil contamination by heavy metals, such as cadmium and zinc demands immediate attention. The dioecious tree Populus cathayana, a phytoremediation plant, plays an important role in rehabilitating heavy metal contaminated areas. In this study, male and female P.

      • Chemical contaminants
      • Heavy Metals
  15. Puerarin prevents cadmium-induced mitochondrial fission in AML-12 cells via Sirt1-dependent pathway

    • Ecotoxicology and Environmental Safety
    • Recent investigations have revealed that puerarin (PU) alleviates cadmium (Cd)-caused hepatic damage via inhibiting oxidative stress. Mitochondria are dynamic organelles and play a critical part in regulating the occurrence of oxidative stress, but the role of mitochondria in the protection of PU against hepatocellular damage caused by Cd exposure remains unknown. Thus, this study was aimed to clarify this issue using mouse hepatocyte AML-12 cell line.

      • Chemical contaminants
      • Heavy Metals
  16. Metabolomic and regular analysis reveal phytotoxic mechanisms of sterigmatocystin in Amaranthus retroflexus L.

    • Ecotoxicology and Environmental Safety
    • Sterigmatocystin (STE) is a common hepatotoxic and nephrotoxic contaminant in cereals, however, its phytotoxicity and mechanisms are poorly understood. Here, the phytotoxic mechanisms of STE were investigated via the metabolomics of Amaranthus retroflexus L. A total of 140 and 113 differential metabolites were detected in the leaves and stems, respectively, among which amino acids, lipids, and phenolic compounds were significantly perturbed.

      • Natural toxins
      • Mycotoxins
  17. Aflatoxin B1 disrupts the intestinal barrier integrity by reducing junction protein and promoting apoptosis in pigs and mice

    • Ecotoxicology and Environmental Safety
    • With the growing diversity and complexity of diet, animals and humans are at risk of exposure to aflatoxin B1 (AFB1), which is a well-known contaminant in the food chain that causes various toxicological effects. The intestine acts as the first barrier against external contaminants, but the effect of AFB1 on intestinal barrier has not been determined.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  18. Physio-biochemical and transcriptomic analysis reveals that the mechanism of Bacillus cereus G2 alleviated oxidative stress of salt-stressed Glycyrrhiza uralensis Fisch. seedlings

    • Ecotoxicology and Environmental Safety
    • Salt stress severely affects the growth and productivity of Glycyrrhiza uralensis. Our previous research found that the endophyte Bacillus cereus G2 alleviated the osmotic and oxidative stress in G. uralensis exposed to salinity. However, the mechanism is still unclear. Here, a pot experiment was conducted to analyse the change in parameters related to osmotic adjustment and antioxidant metabolism by G2 in salt-stressed G.

      • Bacterial pathogens
      • Bacillus cereus
  19. Selection of rice and maize varieties with low cadmium accumulation and derivation of soil environmental thresholds in karst

    • Ecotoxicology and Environmental Safety
    • Cadmium (Cd) is considered the primary dietary toxic element. Previous studies have demonstrated significant differences in heavy metal accumulation among crop species. However, this information in karst areas with low heavy metal activity is missing. In this study, the uptake and accumulation characteristics of cadmium in soil–crop samples of group 504 in the core karst region of East Asia were analyzed.

      • Chemical contaminants
      • Heavy Metals
  20. Toxicity and underlying mechanism of the toxic dinoflagellate Gambierdiscus caribaeus to the fish Oryzias melastigma

    • Ecotoxicology and Environmental Safety
    • Gambierdiscus spp. is mainly responsible for the ciguatera fish poisoning (CFP) around the world. The gambiertoxin produced by Gambierdiscus can be passed through the food chain to form ciguatoxins (CTXs) that cause ciguatoxins poisoning. However, the toxic effects of Gambierdiscus on fish through the food chain and related mechanism remains unclear.

      • Natural toxins
      • Shellfish toxins
  21. Determination of the relative potencies of brominated dioxins for risk assessment in aquatic environments using the early-life stage of Japanese medaka

    • Ecotoxicology and Environmental Safety
    • World Health Organization toxic equivalency factors (WHO-TEFs) are recommended for risk management of brominated dioxins in aquatic environments because limited information is available on their toxicity to fish.

      • Chemical contaminants
      • Dioxins
  22. Lead exposure promotes the inflammation via the circRNA-05280/miR-146a/IRAK1 axis in mammary gland

    • Ecotoxicology and Environmental Safety
    • Lead, the most widely used heavy metal in industry, is detrimental to human health if exposed to living and occupational environment. Although several studies have been conducted on lead exposure, little has been reported on its harm to mammary gland and its mechanisms.

      • Chemical contaminants
      • Heavy Metals
  23. Analysis of the roles of the Notch1 signalling pathway in modulating deoxynivalenol cytotoxicity

    • Ecotoxicology and Environmental Safety
    • Deoxynivalenol (DON) is a trichothecenes produced by fungi that is widespread and poses a threat to human and animal health. The Notch1 signalling pathway is tightly involved in cell fate determination. The aim of this study was to investigate the role of the Notch1 signalling pathway in DON exposure.

      • Natural toxins
      • Mycotoxins
  24. Arsenic inhibits citric acid accumulation via downregulating vacuolar proton pump gene expression in citrus fruits

    • Ecotoxicology and Environmental Safety
    • Citric acid content is a critical quality determinant in citrus (Citrus spp.) fruits. Although arsenic (As) can effectively reduce citric acid content to improve citrus fruit quality, it can have adverse environmental effects. The discovery of nontoxic substitutes is hampered by the incomplete elucidation of the underlying mechanisms of As action in citrus fruits.

      • Chemical contaminants
      • Heavy Metals
  25. Mechanism of mitigating effect of wheat germ peptides on lead-induced oxidative damage in PC12 cells

    • Ecotoxicology and Environmental Safety
    • It is well known that lead-induced neurotoxicity is closely related to oxidative stress. According to previous reports, wheat germ peptides (WGPs) isolated from wheat germ have been shown to have potent antioxidant capacity. This study hypothesized that WGPs could protect PC12 cells from lead-induced oxidative stress.

      • Chemical contaminants
      • Heavy Metals