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Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 151 - 175 of 893

  1. Iron and sulfur reduction caused by different growth seasons inhibits cadmium transfer in the soil-rice system

    • Ecotoxicology and Environmental Safety
    • Effects of iron and sulfur redox states in the soil caused by different growth seasons on Cd uptake by rice remain unclear. In this study, three early rice cultivars and three late rice cultivars were cultivated in a double-cropping system in Cd-contaminated paddy fields.

      • Chemical contaminants
      • Heavy Metals
  2. Cadmium disrupts mouse embryonic stem cell differentiation into ovarian granulosa cells through epigenetic mechanisms

    • Ecotoxicology and Environmental Safety
    • Cadmium (Cd) can influence germ cell development, and epigenetic events may be involved. However, there is no study on whether Cd can influence germ cells differentiation into ovarian granulosa cells (GCs), and more insight into the molecular mechanism of the effect of Cd on germ cell development from mouse embryonic stem (ES) cells into ovarian granulosa cells and investigation of appropriate epigenetic factors are of great importance.

      • Chemical contaminants
      • Heavy Metals
  3. Considerations regarding affinity determinants for aflatoxin B1 in binding cavity of fungal laccase based on in silico mutational and in vitro verification studies

    • Ecotoxicology and Environmental Safety
    • Laccase, a multicopper oxidase, is well known for its industrial potentials to remove environmental pollutants due to its low substrate specificity to oxidize phenols and thus catalytic versatility.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  4. Toxicological responses of juvenile Chinese shrimp Fenneropenaeus chinensis and swimming crab Portunus trituberculatus exposed to cadmium

    • Ecotoxicology and Environmental Safety
    • Cadmium (Cd) is one of the typical metal pollutants in the Bohai Sea. To evaluate the acute toxicological effects of Cd on marine crustaceans, juvenile Fenneropenaeus chinensis and Portunus trituberculatus were exposed to Cd at environmentally relevant concentrations (5 and 50 μg/L) for 96 h. Cd accumulation, antioxidants and metabolite profiles were characterized to elucidate the responses of juvenile crustaceans to Cd stress.

      • Chemical contaminants
      • Heavy Metals
  5. The protective role of MdATG10-mediated autophagy in apple plant under cadmium stress

    • Ecotoxicology and Environmental Safety
    • Autophagy is a conserved degradation pathway in plants, which plays an important role in plant cellular homeostasis during abiotic stress. Although various abiotic stressors have been reported to induce autophagic activity in plants, the specific role of autophagy in plant cadmium (Cd) tolerance remains undiscovered.

      • Chemical contaminants
      • Heavy Metals
  6. Nitric oxide amplifies cadmium binding in root cell wall of a high cadmium-accumulating rice (Oryza sativa L.) line by promoting hemicellulose synthesis and pectin demethylesterification

    • Ecotoxicology and Environmental Safety
    • Nitric oxide (NO) is tightly associated with plant response against cadmium (Cd) stress in rice since NO impacts Cd accumulation via modulating cell wall components. In the present study, we investigated that whether and how NO regulates Cd accumulation in root in two rice lines with different Cd accumulation ability.

      • Chemical contaminants
      • Heavy Metals
  7. Phytoremediation potential of Bermuda grass (Cynodon dactylon (L.) pers.) in soils co-contaminated with polycyclic aromatic hydrocarbons and cadmium

    • Ecotoxicology and Environmental Safety
    • Soils co-contaminated with polycyclic aromatic hydrocarbons (PAHs) and cadmium (Cd) have serious environmental impacts and are highly toxic to humans and ecosystems. Phytoremediation is an effective biotechnology for the remediation and restoration of PAH- and Cd-polluted soils.

      • Chemical contaminants
      • Heavy Metals
  8. Compound probiotics alleviate cadmium-induced intestinal dysfunction and microbiota disorders in broilers

    • Ecotoxicology and Environmental Safety
    • Cadmium (Cd), a common environmental pollutant, seriously threatens the health of intestine. This research aimed to investigate the effects of compound probiotics (CP) on intestinal dysfunction and cecal microbiota dysregulation induced by Cd in broilers. A total of 240 1-day-old Arbor Acre (AA) broilers were randomly assigned to four groups.

      • Chemical contaminants
      • Heavy Metals
  9. Biochar, compost, iron oxide, manure, and inorganic fertilizer affect bioavailability of arsenic and improve soil quality of an abandoned arsenic-contaminated gold mine spoil

    • Ecotoxicology and Environmental Safety
    • Arsenic (As) contaminated mining spoils pose health threats to environmental resources and humans, and thus, mitigating this potential risk is worth investigating.

      • Chemical contaminants
      • Heavy Metals
  10. Rapid determination and dietary intake risk assessment of 249 pesticide residues in Panax notoginseng

    • Ecotoxicology and Environmental Safety
    • UPLC-MS/MS and GC-MS/MS were used to establish a method to simultaneously determine various pesticide residues in Panax notoginseng. Results showed that the limits of detection of 249 pesticides were all 5–10 μg/kg. The detection rate of pesticides in 121 P. notoginseng samples was 93.39%, and 19 pesticides were detected.

      • Chemical contaminants
      • Pesticide residues
  11. Differential expression of genes in C. elegans reveals transcriptional responses to indirect-acting xenobiotic compounds and insensitivity to 2,3,7,8-tetrachlorodibenzodioxin

    • Ecotoxicology and Environmental Safety
    • Caenorhabditis elegans is a well-established model organism for toxicity testing of chemical substances. We recently demonstrated its potential for bioanalysis of the toxic potency of chemical contaminants in water.

      • Chemical contaminants
      • Dioxins
  12. Cadmium induces testosterone synthesis disorder by testicular cell damage via TLR4/MAPK/NF-κB signaling pathway leading to reduced sexual behavior in piglets

    • Ecotoxicology and Environmental Safety
    • Cadmium (Cd) is a highly toxic metal pollutant that can endanger the life and health of animals. Toll-like receptor 4 (TLR4) can result in testicular cell damage by positively regulating mitogen-activated protein kinase (MAPK)/nuclear factor-kappaB (NF-κB) signaling pathway. Meanwhile, Testosterone (T) synthesis disorder can affect sexual behavior.

      • Chemical contaminants
      • Heavy Metals
  13. Valency distributions and geochemical fractions of arsenic and antimony in non-ferrous smelting soils with varying particle sizes

    • Ecotoxicology and Environmental Safety
    • Arsenic and antimony are common toxic metalloids found in associated minerals.

      • Chemical contaminants
      • Heavy Metals
  14. Protective role of curcumin on aflatoxin B1-induced TLR4/RIPK pathway mediated-necroptosis and inflammation in chicken liver

    • Ecotoxicology and Environmental Safety
    • This study set out to assess the mitigative effects of curcumin on AFB1-induced necroptosis and inflammation in chicken liver. Ninety-six one-day-old AA broiler chickens were separated into four groups, including control group, AFB1 (1 mg/kg) group, curcumin (300 mg/kg) + AFB1 (1 mg/kg) group and curcumin (300 mg/kg) group.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  15. Arsenic intake-induced gastric toxicity is blocked by grape skin extract by modulating inflammation and oxidative stress in a mouse model

    • Ecotoxicology and Environmental Safety
    • Arsenic (As) is known to induce toxic responses in many organs of human beings and animals. However, research concerning toxicity in the stomach is limited. In this study, arsenic-induced gastric toxicity was investigated in a mouse model, and grape skin extract (GSE) was confirmed to have protective effects against arsenic toxicity. Our experimental results showed that exposure to 10 mg/l arsenic via drinking water for 56 days caused oxidative damage and inflammatory responses.

      • Chemical contaminants
      • Heavy Metals
  16. Chronic exposure to low-dose cadmium facilitated nonalcoholic steatohepatitis in mice by suppressing fatty acid desaturation

    • Ecotoxicology and Environmental Safety
    • Exposure to cadmium (Cd), a toxic metal, is epidemiologically linked to nonalcoholic steatohepatitis (NASH) in humans. However, the role of Cd in NASH remains to be fully elucidated. This study employed a novel murine NASH model to investigate the effects of chronic low-dose Cd on hepatic pathology and its underlying mechanisms. NASH is characterized by lipid accumulation, extensive cell death, and persistent inflammation in the liver.

      • Chemical contaminants
      • Heavy Metals
      • Viruses
      • Hepatitis
  17. Nitrogen addition alleviated sexual differences in responses to cadmium toxicity by regulating the antioxidant system and root characteristics, and inhibiting Cd translocation in mulberry seedlings

    • Ecotoxicology and Environmental Safety
    • Cadmium (Cd) toxicity and nitrogen (N) deposition are two major environmental stresses which can affect plant growth. It’s less clear that how the combined Cd accumulation and N deposition affect the male and female plants of dioecious species. The aim of the present study was to detect sex-specific responses to Cd stress and simulated N deposition in one-year-old male, female and hermaphrodite seedlings of Morus alba.

      • Chemical contaminants
      • Heavy Metals
  18. Toenail speciation biomarkers in arsenic‐related disease: a feasibility study for investigating the association between arsenic exposure and chronic disease

    • Ecotoxicology and Environmental Safety
    • Long-term exposure to environmental arsenic has been associated with many chronic diseases, including several cancers, and diabetes. Urinary studies have implicated arsenic speciation as an important risk factor, however, such associations have not been replicated using toenail samples: a relatively new biosample for estimating long-term internal dose-exposure to arsenic.

      • Chemical contaminants
      • Heavy Metals
  19. Aflatoxin B1 causes oxidative stress and apoptosis in sheep testes associated with disrupting rumen microbiota

    • Ecotoxicology and Environmental Safety
    • Aflatoxin B1 (AFB1) is an unavoidable environmental pollutant commonly found in feed and foodstuffs. It is the most toxic one of all the aflatoxins, which can cause severe impairment to testicular development and function. Yet, the underlying mechanisms of reproductive toxicity in rams sheep remain inconclusive. The study was designed to explore the effects of AFB1 on sheep testes through rumen-microbiota, oxidative stress and apoptosis.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  20. Low-dose cadmium affects the enantioselective bioaccumulation and dissipation of chiral penflufen in zebrafish (Danio rerio)

    • Ecotoxicology and Environmental Safety
    • Pesticides are currently extensively used in agriculture, forestry, animal husbandry, and environmental hygiene, and their residues have become a global environmental problem, which can easily form combined pollution with heavy metals.

      • Chemical contaminants
      • Heavy Metals
  21. Cadmium transfer between maize and soybean plants via common mycorrhizal networks

    • Ecotoxicology and Environmental Safety
    • More than 80% terrestrial plants establish mutualistic symbiosis with soil-borne arbuscular mycorrhizal fungi (AMF). These fungi not only significantly improve plant nutrient acquisition and stress resistance, but also mitigate heavy metal phytotoxicity, Furthermore, the extraradical mycorrhizal mycelia can form common mycorrhizal networks (CMNs) that link roots of multiple plants in a community.

      • Chemical contaminants
      • Heavy Metals
  22. CORO1A regulates lipoprotein uptake in Leydig cells exposed to cadmium

    • Ecotoxicology and Environmental Safety
    • Cadmium (Cd) is one of the most common environmental pollutants, which has a long biological half-life. Maternal Cd-exposure in the natural environment causes steroidogenesis defects resulting in spermatogenesis disorder in male offspring.

      • Chemical contaminants
      • Heavy Metals
  23. Predicting sustainable arsenic mitigation using machine learning techniques

    • Ecotoxicology and Environmental Safety
    • This study evaluates state-of-the-art machine learning models in predicting the most sustainable arsenic mitigation preference. A Gaussian distribution-based Naïve Bayes (NB) classifier scored the highest Area Under the Curve (AUC) of the Receiver Operating Characteristic curve (0.82), followed by Nu Support Vector Classification (0.80), and K-Neighbors (0.79).

      • Chemical contaminants
      • Heavy Metals
  24. Transcriptional, secondary metabolic, and antioxidative investigations elucidate the rapid response mechanism of Pontederia cordata to cadmium

    • Ecotoxicology and Environmental Safety
    • Pontederia cordata is previously demonstrated a cadmium (Cd) tolerant plant, and also a candidate for the phytoremediation of heavy-metal-contaminated wetlands. A hydroponic experiment was used to investigate variations in photosynthetic gas exchange parameters, antioxidative activities, chlorophyll and secondary metabolite contents, and transcriptome in leaves of the plant exposed to 0.44 mM Cd2+ for 0 h, 24 h, and 48 h.

      • Chemical contaminants
      • Heavy Metals
  25. Feed-additive Limosilactobacillus fermentum GR-3 reduces arsenic accumulation in Procambarus clarkii

    • Ecotoxicology and Environmental Safety
    • Procambarus clarkii (crayfish) accumulates a high concentration of Arsenic (As) from the aquatic environment and causes considerable human health risks. In this study, Limosilactobacillus fermentum GR-3 strain was isolated from “Jiangshui” and applied for As(III) adsorption and antioxidant abilities.

      • Chemical contaminants
      • Heavy Metals