An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 51 - 75 of 247

  1. Transcriptome profiling based on larvae at different time points after hatching provides a core set of gene resource for understanding the immune response mechanisms of the egg-protecting behavior against Vibrio anguillarum infection in Amphi...

    • Fish & Shellfish Immunology
    • Mollusks have recently received increasing attention because of their unique immune systems. Mollusks such as Amphioctopus fangsiao are economically important cephalopods, and the effects of their egg-protecting behavior on the larval immune response are unclear.

      • Bacterial pathogens
      • Vibrio
  2. Src kinase mediates coelomocytes phagocytosis via interacting with focal adhesion kinase in Vibrio splendidus challenged Apostichopus japonicus

    • Fish & Shellfish Immunology
    • Immune cells have many efficient ways to participate in the host immunity, including phagocytosis, which is an important pathway to eliminate pathogens. Only β-integrin-mediated phagocytosis pathways have been confirmed in Apostichopus japonicus. The Src family kinases (SFKs), a class of non-receptor tyrosine kinases plays an important role in the regulation of phagocytic signals in invertebrates. However, the SFK-mediated phagocytic mechanism is largely unknown in A.

      • Bacterial pathogens
      • Vibrio
  3. Dietary supplementation of Bacillus velezensis improves Vibrio anguillarum clearance in European sea bass by activating essential innate immune mechanisms

    • Fish & Shellfish Immunology
    • Bacillus spp. supplementation as probiotics in cultured fish diets has a long history of safe and effective use. Specifically, B.

      • Bacterial pathogens
      • Vibrio
  4. Combined administration routes of marine yeasts enhanced immune-related genes and protection of white shrimp (Penaeus vannamei) against Vibrio parahaemolyticus

    • Fish & Shellfish Immunology
    • Antibiotic usage to control infectious diseases in shrimp aquaculture has led to serious problems on antimicrobial resistance.

      • Bacterial pathogens
      • Vibrio
  5. The potential role of eyestalk in the immunity of Litopenaeus vannamei to Vibrio parahaemolyticus infection II. From the perspective of long non-coding RNA

    • Fish & Shellfish Immunology
    • Long non-coding RNAs (lncRNAs) have been linked to immunological modulation. Unfortunately, little is known about the processes of immune control in shrimp.

      • Bacterial pathogens
      • Vibrio
  6. Protective effects of the biofloc system in Pacific white shrimp (Penaeus vannamei) culture against pathogenic Vibrio parahaemolyticus infection

    • Fish & Shellfish Immunology
    • The mitigation of vibriosis in shrimp culture could be accomplished by reducing the virulence of the pathogen or by increasing the immune response of the shrimp. This study aims to evaluate the application of a biofloc system in protecting Pacific white shrimp (Penaeus vannamei) from pathogenic Vibrio parahaemolyticus infection.

      • Bacterial pathogens
      • Vibrio
  7. Listeria monocytogenes isolates from Cornu aspersum snails: Whole genome-based characterization and host-pathogen interactions in a snail infection model

    • Fish & Shellfish Immunology
    • Even though Listeria monocytogenes is an extensive-studied foodborne pathogen, genome analysis of isolates from snails that may represent a reservoir of Lmonocytogenes are still scarce. Here, we use whole-genome sequencing (WGS) to assess the genomic diversity of hypervirulent, virulent and non-virulent phenotypes of 15 L.

      • Bacterial pathogens
      • Listeria monocytogenes
  8. Transcriptome analysis of Pacific white shrimp (Litopenaeus vannamei) hepatopancreas challenged by Vibrio alginolyticus reveals lipid metabolic disturbance

    • Fish & Shellfish Immunology
    • Vibrio alginolyticus is a devastating bacterial pathogen of Pacific white shrimp (Litopenaeus vannamei), which often causes acute hepatopancreatic necrosis syndrome (AHPNS) and early mortality syndrome (EMS). Elucidation of molecular mechanisms of L. vannamei in responding to infection is essential for controlling the epidemic. In the present study, transcriptomic profiles of L.

      • Bacterial pathogens
      • Vibrio
  9. Bioaccumulation of arsenic and immunotoxic effect in white shrimp (Penaeus vannamei) exposed to trivalent arsenic

    • Fish & Shellfish Immunology
    • Trivalent arsenic (As (III)) contamination in the marine environment can produce adverse effects in crustaceans. The present study investigated the chronic toxicity of As (III) in white shrimp (Penaeus vannamei) by analyzing the tissue bioaccumulation and non-specific immune responses. Shrimps were exposed to 0 (control), 50, 500, and 2500 μg/L of As (III) for 21 days. The results showed that the hepatopancreas was the main tissue of arsenic accumulation in white shrimp.

      • Chemical contaminants
      • Heavy Metals
  10. Toxic effects of waterborne cadmium exposure on hematological parameters, oxidative stress, neurotoxicity, and heat shock protein 70 in juvenile olive flounder, Paralichthys olicaceus

    • Fish & Shellfish Immunology
    • Cadmium-induced toxicity can affect fish embryo development, ion homeostasis regulation, energy metabolism, maturation and growth, stress response, and immunity. However, studies on the toxic effects of cadmium exposure to aquatic animals, particularly olive flounder (Paralichthys olivaceus), are limited. In this study, juvenile P.

      • Chemical contaminants
      • Heavy Metals
  11. An integrin alpha 4 (ChIntα 4) from oyster Crassostrea hongkongensis mediates the hemocytes phagocytosis towards Vibrio alginolyticus

    • Fish & Shellfish Immunology
    • Integrins, a family of cell adhesion transmembrane receptors, mediate cell adhesion, migration, proliferation, apoptosis, and phagocytosis. In the present study, an integrin ChIntα 4 from Crassostrea hongkongensis was characterized to investigate its role in defensing against pathogenic bacterium Vibrio alginolyticus.

      • Bacterial pathogens
      • Vibrio
  12. Transcriptome analysis reveals potential key immune genes of Hong Kong oyster (Crassostrea hongkongensis) against Vibrio parahaemolyticus infection

    • Fish & Shellfish Immunology
    • Hong Kong oyster (Crassostrea hongkongensis) is one of the main species of economic shellfish cultivated in the coastal areas of southern China. The cultivation of this shellfish may be adversely impacted by Vibrio parahaemolyticus, a harmful pathogenic bacterium for many mariculture species, as it usually exists on the surface of Hong Kong oysters.

      • Bacterial pathogens
      • Vibrio
  13. Interleukin-1β enhances the expression of two antimicrobial peptides in grass carp (Ctenopharyngodon idella) against Vibrio mimicus via activating NF-κB pathway

    • Fish & Shellfish Immunology
    • Vibrio mimicus (V. mimicus) is a pathogen causing serious vibriosis in aquatic animals. Hepcidin and β-Defensin1 are two important antibacterial peptides (AMPs) with broad-spectrum antibacterial activity in fish. In mammals, some evidences demonstrated that interleukin-1β (IL-1β) primarily promote AMPs expression via activating classical NF-κB pathway, but it still remains unclear in fish.

      • Bacterial pathogens
      • Vibrio
  14. Effects of microbial community and disease resistance against Vibrio splendidus of Yesso scallop (Patinopecten yessoensis) fed supplementary diets of tussah immunoreactive substances and antimicrobial peptides

    • Fish & Shellfish Immunology
    • This study was conducted to investigate the effects of dietary supplementation of tussah immunoreactive substances (TIS) and antimicrobial peptides (AMPs) on microbial community and resistance against 

      • Bacterial pathogens
      • Vibrio
  15. Intestinal morphology and microflora to Vibrio alginolyticus in pacific white shrimp (Litopenaeus vannamei)

    • Fish & Shellfish Immunology
    • In recent years, the shrimp farming industry encountered significant economic losses induced by Vibrio alginolyticus. In this study, the influence of Vibrio alginolyticus on intestinal histomorphology and microbiome composition in Litopenaeus vannamei were studied.

      • Bacterial pathogens
      • Vibrio
  16. The flagellin of Vibrio parahaemolyticus induces the inflammatory response of Tetraodon nigroviridis through TLR5M

    • Fish & Shellfish Immunology
      • Bacterial pathogens
      • Vibrio
  17. Cadmium regulates FKBP5 through miR-9-5p and induces carp lymphocyte apoptosis

    • Fish & Shellfish Immunology
      • Chemical contaminants
      • Heavy Metals
  18. Phenylalanine hydroxylase (PAH) plays a positive role during WSSV and Vibrio parahaemolyticus infection in Litopenaeus vannamei

    • Fish & Shellfish Immunology
      • Bacterial pathogens
      • Vibrio
  19. Process optimization for fermented siwu decoction by multi-index-response surface method and exploration of the effects of fermented siwu decoction on the growth, immune response and resistance to Vibrio harveyi of Pacific white shrimp (Litop

    • Fish & Shellfish Immunology
      • Bacterial pathogens
      • Vibrio
  20. Identification and characterization of mkk genes and their expression profiles in rainbow trout (Oncorhynchus mykiss) symptomatically or asymptomatically infected with Vibrio anguillarum

    • Fish & Shellfish Immunology
      • Bacterial pathogens
      • Vibrio
  21. Transcriptome analysis of Neocaridina denticulate sinensis challenged by Vibrio parahemolyticus

    • Fish & Shellfish Immunology
      • Bacterial pathogens
      • Vibrio
  22. The potential role of eyestalk in the immunity of Litopenaeus vannamei to Vibrio infection

    • Fish & Shellfish Immunology
      • Bacterial pathogens
      • Vibrio
  23. Bactericidal efficacy of non-thermal plasma activation against Aeromonas hydrophila and immunological responses of koi (Cyprinus carpio haematopterus)

    • Fish & Shellfish Immunology
    • Author(s): Sang Wha Kim, Hyoun Joong Kim, Sang Guen Kim, Jun Kwon, Sung Bin Lee, Won Joon Jung, Young Min Lee, Su Jin Jo, Sib Sankar Giri, Seok Hyun Yoon, Seon Ho Kim, Chan Mo Kim, Cheng Chi, Se Chang Park

      • Bacterial pathogens
  24. A novel ferritin L (FerL) in hybrid crucian carp could participate in host defense against Aeromonas hydrophila infection and diminish inflammatory signals

    • Fish & Shellfish Immunology
    • Author(s): Ning-Xia Xiong, Jie Ou, Shi-Yun Li, Jia-Hui Zhao, Jin-Fang Huang, Ke-Xin Li, Sheng-Wei Luo, Shao-Jun Liu, Ming Wen, Chang Wu, Shi Wang, Kai-Kun Luo, Fang-Zhou Hu, Qing-Feng Liu

      • Bacterial pathogens
  25. Phenylalanine hydroxylase (PAH) plays a positive role during WSSV and Vibrio parahaemolyticus infection in Litopenaeus vannamei

    • Fish & Shellfish Immunology
    • Author(s): Yuanmao Yao, Lili Shi, Wei Xiao, Sixin Guo, Saiya Liu, Haoyang Li, Shuang Zhang

      • Vibrio
      • Bacterial pathogens