Alarm: Next-generation Food-borne Pathogen Detection

Lynntech's overall goal for this project is to develop a diagnostic to detect food-borne pathogens at the point-of-use. We will optimize and fully characterize our convective amplification reaction. In addition, we will refine our mode of detection to include a graphene-based sensor. Last, we will integrate our amplification assay with our graphene-based sensor in the development of a functional cartridge-based prototype that will be tested using "real-life" contaminated food samples. Specific objectives are:1. Optimize and characterize the ALARM convective amplification reaction.2. Develop a modified graphene-based biosensor for the detection of convective PCR products.3. Develop the base unit and food-borne pathogen detection cartridge.4. Validate the ALARM detection system.