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BUILDING IMMUNOPROTEOMICS RESEARCH CAPACITY FOR BIOMARKER DISCOVERY: DETECTION OF PATHOGENIC ANTIGENS IN SWINE LUNG AND ENVIRONMENTAL SAMPLES

Objective

The goal of this integrated research project is to build immunoproteomics research capacity for biomarker discovery. We will acquire updated instrumentation and training and immediately apply these new resources to a competitive research project aimed at identifying swine barn organic dust antigens and the immune cells they activate and/or modulate. We will achieve this goal by completing the following objectives.Objective 1: Enhance training and instrumentation for immunoproteomics studies and biomarker discovery.Objective 2: Investigate functional and phenotypic properties of CD163+ macrophages and other mononuclear cells.Objective 3: Identify immunomodulatory proteins present within the organic dust metaproteome.

Investigators
Waterman, J.
Institution
North Carolina A&T State University
Start date
2020
End date
2023
Project number
NC.X2019-03190
Accession number
1021764