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This research project aims to improve our understanding of how one group of harmful chemicals sometimes found in food may cause cancer.
<p>This project will investigate the effects of a chemical representative of a class of harmful substances found in food on cellular (e.g. cell growth and survival) and genomic (e.g. gene mutation and expression) processes.
<p>The analysis will be performed in cultured cells from the tissue in which the harmful chemical can cause cancer and also in cells from an alternative tissue.
<p>The effects of the chemicals on gene expression in target and non-target tissues will also be investigated in a second experimental model system.
Some harmful chemicals found in food may cause cancer. However, the possible mechanisms involved remain poorly understood.
<p>This project aims to identify the key events that take place during the initial stages of the carcinogenic process.
<p>Find more about this project and other FSA food safety-related projects at the <a href="http://www.food.gov.uk/science/research/" target="_blank">Food Standards Agency Research webpage</a>.