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National Agricultural Library
U.S. Department of Agriculture
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  4. Co-Display of Hemagglutinin and CD154 on the Surface of Yeast Cells as a Vaccine Against Avian Influenza

Co-Display of Hemagglutinin and CD154 on the Surface of Yeast Cells as a Vaccine Against Avian Influenza

Objective

<p>
<ol>
<li>Generate HA surface-presented yeast recombinant avian influenza vaccines.</li>
<li>Characterize humoral and cellular-mediated immune responses of yeast vaccines in mice.</li>
<li>Demonstrate protection of mice from lethal avian-influenza virus through yeast-based immunization.</li></ol></p>

More information

Responsible Division: Microbiology

Investigators
Hart, Mark
Institution
DHHS/FDA - National Center for Toxicological Research
Funding Source
Nat'l. Center For Toxicological Research
Project number
E0733301
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