<p>
<ol>
<li>Determine the pharmacokinetics of the production of urinary metabolites of DEHP and BPA after cardiopulmonary bypass (CPB) in children.</li>
<li>In a pilot study, quantify the exposure of children to DEHP and BPA while undergoing CPB compared to critically ill children without cardiac surgery and healthy controls.</li>
<li>Evaluate the ability of urinary biomarkers to detect acute kidney injury in patients following CPB.</li></ol></p>
Responsible Division: Biochemical Toxicology