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National Agricultural Library
U.S. Department of Agriculture
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  4. Di(2-ethylexl)phthalate (DEHP) and Bisphenol A (BPA) Exposure in Pediatric Patients

Di(2-ethylexl)phthalate (DEHP) and Bisphenol A (BPA) Exposure in Pediatric Patients

Objective

<p>
<ol>
<li>Determine the pharmacokinetics of the production of urinary metabolites of DEHP and BPA after cardiopulmonary bypass (CPB) in children.</li>
<li>In a pilot study, quantify the exposure of children to DEHP and BPA while undergoing CPB compared to critically ill children without cardiac surgery and healthy controls.</li>
<li>Evaluate the ability of urinary biomarkers to detect acute kidney injury in patients following CPB.</li></ol></p>

More information

Responsible Division: Biochemical Toxicology

Investigators
Doerge, Daniel
Institution
DHHS/FDA - National Center for Toxicological Research
DHHS/FDA- Center for Devices and Radiological Health
Funding Source
Nat'l. Center For Toxicological Research
Project number
E0742501
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