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National Agricultural Library
U.S. Department of Agriculture
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  4. DIETARY XANTHOPHYLLS IN PREVENTING INFLAMMATION AND PROMOTING GUT HEALTH

DIETARY XANTHOPHYLLS IN PREVENTING INFLAMMATION AND PROMOTING GUT HEALTH

Objective

1) Evaluate the anti-inflammatory properties of astaxanthin-enriched salmon via rebalancing of human gut microbioment in obese prediabetic human subjects, and test the role of diet-induced guy microbiome alteration on inflammation in germ-free mice.2)Determine the underlying metabolic mechanism by which astaxanthin, as one of the salmon bioactive compounds, exerts the anti-inflammatory role through regulating certain aspects of gut microbiome growth, metabolism, and function in obese prediabetic BCO2/db/db double knockout mice.

Investigators
Lin, D.; Conway, Ty, .; Hermann, Ja, .; Tang, Mi, .; Von Lintig, Jo, .
Institution
Oklahoma State University
Start date
2020
End date
2023
Funding Source
Nat'l. Inst. of Food and Agriculture
Project number
OKL03184
Accession number
1022146
Commodities
Seafood
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