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National Agricultural Library
U.S. Department of Agriculture
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  4. Effect of Ethanol on the Tumorigenicity ofUrethane (Ethyl Carbamate) in B6C3F1 Mice

Effect of Ethanol on the Tumorigenicity ofUrethane (Ethyl Carbamate) in B6C3F1 Mice

Objective

To determine the effect of ethanol on the tumorigenicity of urethane (ethyl carba-mate)in B6C3F1 mice.

More information

FY 2000 Accomplishments:1) Draft pathology report completed.2) Metabolism/adduct study continued.3) Two papers on mass spectrometry methods for the detection of etheno DNAadducts submitted.FY 2001 Plans:1) Prepare draft NTP final report.2) Complete mechanistic studies associated with bioassay.2) Initiate oncogene analyses.

Investigators
Beland, Frederick
Institution
DHHS/FDA - National Center for Toxicological Research
Funding Source
Nat'l. Center For Toxicological Research
Project number
E0212001