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<p>1.Determine the environmental factors that must be modified to prevent the early establishment of Salmonella in food production environments and virulence expression under these conditions;</p>
<p>2.Study the metabolism of Salmonella spp. under anaerobic conditions to better understand what factors are required for successful Salmonella spp. establishment in food production animals;</p>
<p>3.Screen potential prebiotic compounds that would promote beneficial bacteria in the gastrointestinal tract for humans and animals.</p>
<p>NON-TECHNICAL SUMMARY:<br/> Salmonellosis is one of the most common foodborne diseases with a range anywhere from 1 to 4 million human infections reported each year in the United States. Further, it is one of the more costly foodborne diseases in the U.S. Given that foodborne Salmonella spp. can originate from a wide variety of food production environments, reduction of this organism at all stages of food production is critical. This project's research program reflects an integrated approach for controlling Salmonella spp. and other foodborne pathogens by examining virulence expression of Salmonella under typical food production and processing conditions.
<p>APPROACH:<br/> The idea here is to compare anaerobic and aerobic growth and pathogenic responses of foodborne Salmonella spp. The hypothesis is that Salmonella may physiologically behave differently when grown under one environmental condition versus the other. Our food production Salmonella spp. research projects will emphasize studies on the growth, survival and pathogenesis of Salmonella spp. under conditions encountered during food animal production and processing. We will also examine virulence activity of Salmonella spp. under these conditions.</p>
<p>PROGRESS: <br/>2012/10 TO 2013/09Target Audience: Poultry and food commodity groups, poultry growers, poultry processors Changes/Problems: Nothing Reported What opportunities for training and professional development has the project provided? Nothing Reported How have the results been disseminated to communities of interest? Presented invitedtalks to a wide range of audeinces both nationally and internationally. What do you plan to do during the next reporting period to accomplish the goals? Continue research projects.</p>