GASTROINTESTINAL ABSORPTION OF 14C-LABELED FEED ADDITIVES

The overall objective of this study is to evaluate effects of a slow-release formulation on the in vivo rates of gastrointestinal absorption of an organic acids that is an effective anti-bacterial agent in broiler chicks and rats. Specific objectives are: 1) To determine the rates and sites of organic acid absorption with and without formulation on proprietary beads in broiler chicks and rats. 2) To determine the in vitro kinetics of organic acid release from formulated beads under various conditions (temperature, pH, mechanical grinding, etc.).