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Gene-targeted mice expressing human PrP to assess zoonosis of CWD and other animal prions

Objective

To develop more precise gene-targeted mouse models expressing human prion protein, either M129, or V129 to assess potential zoonotic transmission of chronic wasting disease prionand other animal prions.

Investigators
Bian, Jifeng
Institution
Colorado State University
Start date
2019
End date
2021
Project number
COLV2019-03
Accession number
1020162