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The goals of this K23 award are to provide a training platform for Corinne Keet, MD, MS to become an independent investigator performing patient-oriented research in the field of allergy and immunology, and to explore the mechanisms of the development of food allergy, a disease that affects approximately 5% of children. In two pediatric cohorts, we will examine (1) two candidate gene pathways for food allergy, the skin barrier and vitamin D, (2) interactions between these pathways and season of birth, and (3) the effects of season of birth on early life skin barrier and vitamin D. The findings from this study may inform preventative strategies for food allergy.
The goals of this K23 award are to provide a training platform for Corinne Keet, MD, MS to become an independent investigator performing patient-oriented research in the field of allergy and immunology, and to explore the mechanisms of the development of food allergy, a disease that affects approximately 5% of children. In two pediatric cohorts, we will examine (1) two candidate gene pathways for food allergy, the skin barrier and vitamin D, (2) interactions between these pathways and season of birth, and (3) the effects of season of birth on early life skin barrier and vitamin D. The findings from this study may inform preventative strategies for food allergy.