Genome Sequencing, Analysis, and Functional Genomic Studies of Aspergillus Flavus

A) Sequencing and analysis of the whole genomes of additional aflatoxin-producing Aspergillus (A.) strains including both L and S type strains from A. flavus and A. parasiticus for genome wide comparison on their genome structure, gene sets, and gene functions; B) Identify gene and sets of genes involved in genetic regulation on aflatoxin formation, sclerotia development and pathogenecity; and C) Using Next Generation sequencing technologies to study fungus – plant (crop) interaction and to identify genes and factors that confer resistance against fungal infection in crops such as peanut or corn for devising strategies to eliminate or reduce aflatoxin contamination in food and feed.