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Global Health and Environmentally-Induced Birth Defects: Biomarkers & Mechanisms of Gestational Fumonisin Exposure & Neural Tube Defects

Objective

Determine the role of fumonisin exposure in the high incidence of neural tube defects (NTDs) in consumers of maize products.

More information

Approach:
Utilize information developed from Creighton University studies in mouse models to assess and validate the use of sphingolipid and genetic mechanism-based and fumonisin exposure-based biomarkers in women from populations known to consume large amounts of maize potentially contaminated with fumonisin.

Investigators
Riley, Ronald
Institution
USDA - Agricultural Research Service
Start date
2010
End date
2014
Project number
6040-42000-012-01R
Accession number
420651