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National Agricultural Library
U.S. Department of Agriculture
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  4. Global Identification of Genes Regulated by luxS- Based Quorum Sensing in Salmonella

Global Identification of Genes Regulated by luxS- Based Quorum Sensing in Salmonella

Objective

Our knowledge and understanding of the luxS-based quorum sensing system in Salmonella is minimal. Preliminary data obtained from this laboratory has identified phenotypes for Salmonella luxS mutants and these will be investigated further. Genes regulated by luxS in Salmonella will be identified using genome-wide lacZ transcriptional fusions and DNA microarrays. Finally, the role of luxS in virulence and immunity in vivo will be determined.

Institution
University of Newcastle upon Tyne
Start date
2003
End date
2006
Funding Source
Biotechnology and Biological Sciences Research Council
Project number
D17313
Categories
Viruses and Prions
Salmonella