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HUMAN SUSCEPTIBILITY TO TRICHOTHECENE MYCOTOXINS

Objective

Complete studies on the sensitivity of blood leukocytes from different human donors to DON-induced stress activation and cytokine upregulation. Identify threshold doses of DON required for stress activation and cytokine upregulation in the mouse and corresponding DON tissue levels.

Investigators
Simmons M W
Institution
Michigan State University
Start date
2004
End date
2009
Project number
0500-00053-002-14G
Accession number
408361