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National Agricultural Library
U.S. Department of Agriculture
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  4. The impact of host-pathogen interactions on genomic integrity and oncogenesis

The impact of host-pathogen interactions on genomic integrity and oncogenesis

Objective

Aim 1.1 Determine the impact of conflict resolution factors on DNA damage signaling during Lm infectionAim 1.2: Determine the impact of conflict resolution factors on interactions between RNA polymerase and the DNA replication machinery during Lm infectionAim 1.3: Determine the chromosomal locations of DNA damageAim 2.1: Measure R-loop levels in Lm infected cells and quantify the contribution of R-loop resolution factors?Aim 2.2 Determining chromosomal locations of R-loops in Lm infected human cells

Investigators
May, Alexa
Institution
WEAVER LABS LLC
Start date
2023
End date
2024
Funding Source
Nat'l. Inst. of Food and Agriculture
Project number
OKLW-2023-00804
Accession number
1030094
https://portal.nifa.usda.gov/web/crisprojectpages/1030094.html