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IMPROVEMENT OF CRISPR/CAS9-MEDIATED GENOME EDITING IN POULTRY

Objective

The main goal is to develop a new method for easily and efficiently generating genome edited avian species without mediating current methods using a primordial germ cell (PGC)-mediated approach.The main objective of the proposal is to generate GE poultry species by injecting CRISPR/Cas9 adenovirus into four specific locations in specific developmental stages of embryogenesis and to provide an efficient next-generation method for genome-editing in poultry.

Investigators
Lee, K.
Institution
Ohio State University
Start date
2020
End date
2022
Project number
OHO03063-CG
Accession number
1022876