Hepatitis E Virus (HEV) is the main cause of acute viral hepatitis in the world, resulting in substantial maternal and newborn morbidity and mortality, primarily in South Asia. This prospective, population-based research will determine the disease burden and consequences of infection, and study the immunopathogenesis of HEV in 10,000 pregnant women and their newborn infants in South Asia. This will establish the foundation for population-level interventions (eg. vaccines) to improve maternal and infant survival in resource-poor settings.
Incidence and Natural History of Hepatitis E Virus in Pregnant Bangladeshi Women
Objective
Investigators
Labrique, Alain Bernard
Institution
Johns Hopkins University
Start date
2010
End date
2011
Funding Source
Project number
1R56AI068813-01A2
Categories