INTEGRATED BIOSENSOR-BASED PROCESSES FOR MULTIPATHOGENIC ANALYTE DETECTION

The ultimate goal of this project is to develop rapid, specific, and sensitive biosensor-based assays for diverse pathogenic bacteria which can be widely adopted in applications ranging from simple field tests to high speed, high throughput laboratory screening assays. To meet this goal, several objectives will be pursued: 1) Develop specific, high affinity biorecognition reagents for food-borne pathogens and toxins. 2) Develop rapid and effective means to separate and concentrate targeted pathogens without carryover of background organisms. 3) Develop integrated assay systems based on multiple target biosensor platforms.