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National Agricultural Library
U.S. Department of Agriculture
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  4. Laboratory Assessment of Respiratory Risk for Highly Pathogenic Avian Influenza Virus

Laboratory Assessment of Respiratory Risk for Highly Pathogenic Avian Influenza Virus

Objective

<ol>
<li> To determine pathogenesis of aerosol exposure to highly pathogenic avian influenza (HPAI) viruses in a ferret model, and
<li> To develop protocols and test the stability of HPAI viruses in different environments and conditions.

More information

Five pathogenicity avian influenza virus (HPAI) will be examined for potential to produce infection in ferret model following aerosol exposure. The evaluation will include varying particle size for exposure and determine infection and pathogenicity by virus isolation, histopathology and immunohistochemistry. The HPAI viruses will be studied under different temperatures and humidity conditions to determine environmental survivability.

Investigators
Suarez, David
Institution
USDA - Agricultural Research Service
Start date
2007
End date
2009
Funding Source
Nat'l. Inst. of Food and Agriculture
Project number
6612-32000-048-20R
Accession number
411537
Categories
Bacterial Pathogens
Sanitation and Quality Standards
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