EmergingDx, Inc. in collaboration with its academic partner will design and develop a rapid, low-cost, multiplexed, colorimetric, quantitative loop-mediated isothermal amplification (qLAMP) microfluidic based diagnostic device with high sensitivity and selectivity for screening reproductive fluids/gametes to be used for breaking the vertical transmission of pathogens in aquaculture.In Phase I period, we will develop and demonstrate a paradigm shift concept for detection of fish pathogens. EmergingDx's proposed colorimetric microfluidic based diagnostic device involves (i) adapting its academic partner'sexisting laboratory style LAMP assay capable of identifying Flavobacterium psychrophilum in ovarian fluid and milt, (ii) a self-contained, robust, rapid, low-cost, low power, hand-held novel microfluidic device, and (iii) colorimetric detection and data analytics with a phone app for quantification and data storage/transmission. Expected benefits, key risk areas, their associated mitigation strategies, and reliability estimates will be identified and continually reassessed.
LOW-COST DIAGNOSTIC PLATFORM FOR AQUACULTURE
Objective
Investigators
Unal, B.; Loch, TH, .
Institution
EMERGINGDX INC
Start date
2023
End date
2024
Funding Source
Project number
MASW-2023-00981
Accession number
1030071