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Mechanism of Secretion Activation in the Shigella TTSS

Objective

Gram-negative bacteria commonly interact with eukaryotic host cells by using type III secretion systems (TTSSs or secretons). TTSSs serve to inject bacterial proteins directly into the host cell membrane and cytoplasm during infection.

Institution
University of Oxford
Start date
2005
End date
2008
Project number
G0401595
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