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U.S. Department of Agriculture
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  4. MECHANISMS UNDERLYING SUSCEPTIBILITY OR RESISTANCE OF ANIMAL SPECIES TO SARS-COV-2

MECHANISMS UNDERLYING SUSCEPTIBILITY OR RESISTANCE OF ANIMAL SPECIES TO SARS-COV-2

Objective

The overarching goals of the proposed study are to assess the host range of SARS-CoV-2 and determine the mechanisms underlying species susceptibility or restriction to SARS-CoV-2 infection. The specific aims of the proposed study are: Aim 1:To identify the mechanisms underlying SARS-CoV-2 host range and animal species specificity at the cellular level;Aim 2: To characterize the factors affecting SARS-CoV-2 susceptibility at the organism level; and Aim 3: To investigate natural exposure and susceptibility of farm animals to variant SARS-CoV-2 strains through surveillance.

Investigators
Diel, D. G.; Lager, KE, M..; Buckley, AL, .; Cunningham, JE, LE.
Institution
CORNELL UNIVERSITY
Start date
2023
End date
2026
Funding Source
Nat'l. Inst. of Food and Agriculture
Project number
NYCV478-923
Accession number
1030048
https://portal.nifa.usda.gov/web/crisprojectpages/1030048.html