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To carry out experiments to determine target animal safety, dose titration, shelf life- and upscale field evaluations of MSC® and compare results to MCE trials.
To provide microbiological cultures as may be needed in quantity and time to conduct the research described; to carry out titration studies to determine minimum effective dose levels of MSC(TIM) cultures; Determine target animal safety of MSC® cultures; Compare the efficacy of MSC® cultures increased by Continental for upscale field evaluation and demonstration with that of ARS' starter cultures; Determine the shelf-life of starter cultures and MSC® cultures under various storage conditions; Provide advice and counsel as may be needed in conducting upscale field evaluations and demonstrations; and assist in determining the efficacy MSC® cultures in reducing or prevention of intestinal colonization of broilers by Salmonlla in upscale field anddemonstration trials. CRADA with Continental Grain Company.