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National Agricultural Library
U.S. Department of Agriculture
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  4. MULTIPLEXED GENE EDITING IN LIVESTOCK EMBRYONIC STEM CELLS

MULTIPLEXED GENE EDITING IN LIVESTOCK EMBRYONIC STEM CELLS

Objective

Our overall goal is to develop a platform for efficient multiplexed genome editing in livestock species. Our specific objectives are:1. To optimize CRISPR-Cas9 delivery and genome editing reagents for efficient gene disruption, allele introgression, and targeted gene insertion, in bovine, ovine and caprine ESCs.2. To optimize conditions for multiplexed gene editing in cattle ESCs.

Investigators
Ross, P. J.
Institution
University of California - Davis
Start date
2020
End date
2022
Funding Source
Nat'l. Inst. of Food and Agriculture
Project number
CA-D-ASC-2598-CG
Accession number
1022769
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