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National Agricultural Library
U.S. Department of Agriculture
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  4. A PARTNERSHIP IN THE MAKING: MATCHING FIBER WITH BUTYRATE-PRODUCING BACTERIA TO PREVENT ATHEROSCLEROSIS

A PARTNERSHIP IN THE MAKING: MATCHING FIBER WITH BUTYRATE-PRODUCING BACTERIA TO PREVENT ATHEROSCLEROSIS

Objective

The main goal of this project is to test the causal relationship between butyrate-producing bacteria (BPB), dietary fiber, and development of metabolic and vascular disease. We hypothesize that microbial-derived butyrate constitutes a protective mechanism against atherosclerotic plaque formation. Our specific aims are:1a. Test the contributions of five prominent butyrogenic species on metabolic and vascular disease;1b. Identify dietary substrates that enhance beneficial effects of butryrogenic bacteria.

Investigators
Rey, Fe, Eu.; Rey, Fe, .
Institution
University of Wisconsin - Madison
Start date
2020
End date
2024
Funding Source
Nat'l. Inst. of Food and Agriculture
Project number
WIS03073
Accession number
1022872
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