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POLYPHENOL-RICH FOODS AND PROMOTION OF INTESTINAL HEALTH

Objective

Objective 1: Determine if polyphenol rich diets prevent microbiome dysbiosis, inappropriate activation of Toll and NOD-like receptor (TLR/NOD-like receptors) and reduce the severity of colitis in pigs. [NP107, C3, PS3B] Objective 2: Compare consumption of polyphenol-rich foods combined with probiotics early in life for amelioration of systemic inflammation induced by a westernized high fat diet. [NP107, C3, PS3B, C4, PS4A] Objective 3: Establish if consumption of polyphenol-rich foods will normalize westernized high fat diet-induced microbiome dysbiosis and prevent generalized inflammation. [NP107, C3, PS3B C4, PS4A]

Investigators
Solano-Aguilar, Gloria; Urban, Joseph; Dawson, Harry
Institution
USDA - Agricultural Research Service
Start date
2019
End date
2024
Project number
8040-51530-058-00D
Accession number
436294