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Production of Transgenic Mice

Objective

Production of transgenic mice carrying the following prion proteins: 1) Porcine Prion Protein 2) Mutant Bovine Prion Protein

More information

APPROACH: The prion protein (PrP) genes of mice will be manipulated using transgenesis, inserting either porcine prion protein or mutant bovine prion protein within the background of a prion protein knock out mouse.

Investigators
Telling, Glenn; Greenlee, Justin
Institution
University of Kentucky
USDA - Agricultural Research Service
Start date
2007
End date
2009
Project number
3625-32000-086-13S
Accession number
412474