Protective Effect of Antioxidants against Ochratoxin A in Infant Cereals

The long-term goal of our research is to improve food safety by reducing the risk of exposure to OTA in cereal-based foods. The goal of this study is to investigate the efficacy of antioxidants in reducing OTA mediated toxicity to protect infants, a high-risk population.We propose to achieve the goals by pursuing the specific objectives below.Evaluation of protective effect of antioxidants against OTA by in vitro bioassay using mammalian cell culture.Confirmation of protective effects of selected antioxidants against OTA by in vivo bioassay using a mouse model.