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Quantification Proteomic, Transcriptomic, and Phenotypic Microarray Analysis of C. Jejuni for the Identification of Colonization Factors in Poultry

Objective

<p>
<ol>
<li>Evaluate genomic and phenotypic microarrays, and whole proteomic analyses to compare genes, phenotypes, and proteins from both good and poor C. Jejuni chicken colonizers.</li>
<li>Investigate functional role of identified colonizing factors by mutant construction, in vitro assays, and in vivo assays.</li>
<li>Identify potential targets for vaccine that will enable us to eliminate the threat of Campylobacter infection in chickens.</li></ol></p>

More information

Responsible Division: Microbiology

Investigators
Sung, Kidon
Institution
DHHS/FDA - National Center for Toxicological Research
Project number
E0735601
Commodities