Safety Assessment RP226 Xygest HT

An application was submitted to the Food Standards Agency in February 2021 from Kemin Europa N.V. (“the applicant”) for the authorisation of an additive (endo-1,4- beta-xylanase-Xygest ® HT), under the category of ‘zootechnical’ additives, functional group ‘digestibility enhancers’ for all poultry. To support the Food Standards Agency (FSA) and Food Standards Scotland (FSS) in evaluating the dossier, the Animal Feed and Feed Additives Joint Expert Group (AFFAJEG) and the Advisory Committee on Animal feedingstuffs (ACAF) were asked to review the dossier and the supplementary information from the applicant. The ACAF concluded that the additive was correctly identified and characterised. No causes for concern were raised in this section of the application. The ACAF concluded that the additive can be considered safe for the target species, with a margin of safety of 300 for growing poultry and 25 for laying poultry. The additive can be considered safe for consumers and the environment. The additive should be considered a respiratory sensitiser. The additive is not an eye irritant, skin irritant or skin sensitiser. Based on data from four trials in growing poultry and five trials in laying poultry, the ACAF concluded that the additive Xygest® HT can be considered to be efficacious in laying poultry and growing poultry. Conclusions can be extrapolated to all poultry. The views of AFFAJEG and ACAF have been taken into account in the safety assessment which represents the opinion of the FSA and FSS.