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National Agricultural Library
U.S. Department of Agriculture
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  4. Selection of Defense Peptides to Protect Wheat from Fusarium Head Blight

Selection of Defense Peptides to Protect Wheat from Fusarium Head Blight

Objective

Apply newly developed plant defense technologies to the protection of wheat from scab caused by Fusarium species. Technologies include, methods for selection of peptides that bind to and disrupt the development of infective structures of invasive pathogens, and means of delivering disruptive defense peptides in transgenic plants via fusion to a scaffold protein.

More information

Approach: Select peptides that bind to pathogen structure from combinational libraries of one billion or more random peptide sequences. Evaluate the ability of recovered binding peptides to inhibit germination and growth of F. graminearum macroconidia and germlings representative of diverse isolates.

Investigators
Walker-Simmons, M. Kay
Institution
University of Missouri - Columbia
USDA - Agricultural Research Service
Start date
2007
End date
2009
Funding Source
Agricultural Research Service
Project number
0500-00053-002-64G
Accession number
411912