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Use of CRISPR-equipped Engineered Phage for the Control of Persistent Listeria Monocytogenes

Objective

Aim 1To engineer a panel of CRISPR-equipped synthetic Listeria phage that can be utilized to specifically target and eliminate Listeria.Aim 2To functionally assess and validate the efficacy of CRISPR-equipped engineered synthetic phage against Listeria monocytogenesof diverse genotypes and serotypes, as well as other Listeria species.

Investigators
Kathariou, Sophia
Institution
North Carolina State University
Start date
2019
End date
2022
Project number
NC09865
Accession number
1019041
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