Research Publications (Food Safety)

Large differences in COVID‐19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe or the Balkans have a common feature of eating large quantities of fermented foods. Although biases exist when examining ecological studies, fermented vegetables or cabbage were associated with low death rates in European countries. SARS‐CoV‐2 binds to its receptor, the angiotensin converting enzyme 2 (ACE2).

There is paucity of evidence assessing immune responses to COVID‐19 in severe asthmatics treated with biologics. Recent guidelines recommend continuing these agents (as clinically indicated) to maintaining asthma control.

After adjusting for confounding factors, COVID‐19 patients with COPD have higher risks of developing severe illness and acute respiratory distress syndrome than COVID‐19 patients with asthma. COPD patients have increased, whereas asthmatics have decreased ACE2 protein expression in lower airways, compared with that in control subjects without asthma and COPD. IL‐17A, TNF‐α, and IL‐12 promote, while IL‐4 and IL‐13 suppress ACE2 expression in airway BEAS‐2B cells.

The pandemic condition coronavirus disease (COVID‐19), caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), can take asymptomatic, mild, moderate, and severe courses. COVID‐19 affects primarily the respiratory airways leading to dry cough, fever, myalgia, headache, fatigue, and diarrhea and can end up in interstitial pneumonia and severe respiratory failure.

Aims Providing a ready‐to‐use reverse transcriptase qPCR (RT‐qPCR) method fully validated to detect the SARS‐CoV‐2 with a higher exclusivity than this shown by early published RT‐qPCR designs. Methods and Results The specificity of the GPS™ CoVID‐19 dtec‐RT‐qPCR test by analysis of sequence alignments was approached and compared with other RT‐qPCR designs. The GPS™ CoVID‐19 dtec‐RT‐qPCR test was validated following criteria of UNE/EN ISO 17025:2005 and ISO/IEC 15189:2012.

In this study, the anti–severe acute respiratory syndrome coronavirus‐2 (anti‐SARS‐CoV‐2) activity of mycophenolic acid (MPA) and IMD‐0354 was analyzed. These compounds were chosen based on their antiviral activities against other coronaviruses. Because they also inhibit dengue virus (DENV) infection, other anti‐DENV compounds/drugs were also assessed.

We outline the unfavorable circumstances in stroke care induced by the SARS‐CoV‐2/COVID‐19 pandemic, propose mitigating measures, crisis management, and provide a comparative evaluation of stroke care between India and United States during the pandemic. Abstract Stroke care in India has evolved rapidly in the last decade with a focus on stroke awareness, prevention, rapid triage, treatment, and rehabilitation.

This editorial considers the persisting importance of rhetoric and equity in health policy analysis, implementation, and outcomes. It argues that employing social determinants of health, and intersectional and rhetorical frames, can improve life and health outcomes, as measured by morbidity and mortality. The pertinence of these frames with regard to the crises brought on by the COVID‐19 pandemic is discussed, and the plan for a special issue on disparties and COVID‐19 is announced.

Although the exact origin of SARS‐CoV‐2, the etiologic agent of COVID‐19, is currently unknown, there is substantial evidence to suggest the source of transmission of the virus occurred within the Wuhan wet market. In these markets, bats and wild animals are frequently sold and stored in close contact. During several of the world's past pandemics, bats were essential to the spread of zoonotic diseases from bat to another animal or to humans directly.

COVID‐19 presents an existential challenge for millions of people and a generational challenge for the globe. Scientific research is the primary vehicle in humanity's attempts to understand the virus and mitigate its effects. Research on the pathogen is critically important. At the same time, COVID‐19's consequences are due to more than the pathogen.

The COVID‐19 pandemic has brought renewed attention to the lack of urban planning and its public health implications in developing countries. Slum communities face the dual challenges of chronically poor residential environments and the acute effects of a pandemic and the preventive measures that follow.

An emerging infectious disease event like the coronavirus (COVID‐19) pandemic demands careful communication of public health messages to diverse audiences. However, misinformation is easily generated and amplified when a rapidly evolving epidemiological situation is coupled with gaps in scientific knowledge about a novel pathogen.

In spite of presumed readiness to confront infectious disease outbreaks, the United States was unprepared for the advent of the novel Coronavirus disease (COVID‐19) in the early months of 2020. The response was slow, mired in ad hoc responses, lack of planning, challenges in supply chains and human resources, and discord in balancing public health measures with economic considerations arising from far‐reaching disruptions in various sectors. The lessons learned derive from such challenges.

Many jurisdictions enacted stay‐at‐home orders (also called shelter‐in‐place orders, safer‐at‐home orders, or lockdowns) when SARS‐CoV‐2 began spreading in the United States. Based on Google mobility data, every state had substantially fewer visits to transit stations, retail and recreation facilities, workplaces, grocery stores, and pharmacies by the end of March 2020 than in the previous two months.

COVID‐19 temporarily severed the production and the supply chains for fentanyl, a synthetic narcotic responsible for over 30,000 deaths in the United States in 2018. Much fentanyl was produced in Wuhan, China, the source of the epidemic. Fentanyl was previously sold directly to American consumers through online websites and was also supplied by Mexican drug traffickers, who produced the drug from precursor chemicals purchased from China.

Racial disparities are apparent in the impact of coronavirus disease 2019 (COVID‐19) in the United States, yet the factors contributing to racial inequities in COVID‐19 mortality remain controversial. To better understand these factors, we investigated racial disparities in COVID‐19 mortality among America's essential workers.

A lesson learned from decades of research is that businesses and nonprofits can form private partnerships to serve the public good. One such partnership is a cause‐related marketing campaign, where a business donates a portion of its sales to a nonprofit to address a social need.

The novel coronavirus pandemic poses unique challenges to forcibly displaced populations around the world. Months into the pandemic, countries are still scrambling to enact policies that mitigate the outbreak and minimize the strain on their health‐care infrastructures and economies. The United Nations High Commissioner for Refugees continues to work with member states to provide guidance and assistance to those populations protected under their mandate.