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Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 10151 - 10175 of 42094

  1. Prevalence and molecular characterization of antibiotic resistance and associated genes in Klebsiella pneumoniae isolates: A clinical observational study in different hospitals in Chattogram, Bangladesh

    • PLOS ONE
    • by Afroza Akter Tanni, Md. Mahbub Hasan, Nahid Sultana, Wazir Ahmed, Adnan Mannan

      Objective

      This study was performed to investigate the prevalence of multidrug resistance and molecular characterization of Klebsiella pneumoniae (KPN) from clinical isolates in the southern region of Bangladesh. Additional analysis of the prevalence of blaNDM-1, blaSHV-11, uge genes of KPN was also carried out among these clinical isolates.

      Method

      • Bacterial pathogens
  2. Metal organic framework based fluorescence sensor for detection of antibiotics

    • Trends in Food Science & Technology
    • Author(s): Murugavelu Marimuthu, Selva Sharma Arumugam, Devaraj Sabarinathan, Huanhuan Li, Quansheng Chen

  3. Toxic effects of subacute exposure to acrylamide on motor endplates of the gastrocnemius in rats

    • Toxicology
    • Author(s): Bai Yanxian, Ziting Gu, Tong Zhang, Yuyou Luo, Chunmei Zhang, Li Luo, Yuxin Ma, Jing Liu

      • Chemical contaminants
  4. Enhanced Bio-Barcode Immunoassay Using Droplet Digital PCR for Multiplex Detection of Organophosphate Pesticides

    • Journal of Agricultural and Food Chemistry
    • A bio-barcode immunoassay based on droplet digital polymerase chain reaction (ddPCR) was developed to simultaneously quantify triazophos, parathion, and chlorpyrifos in apple, cucumber, cabbage, and pear. Three gold nanoparticle (AuNP) probes and magnetic nanoparticle (MNP) probes were prepared, binding through their antibodies with the three pesticides in the same tube. Three groups of primers, probes, templates, and three antibodies were designed to ensure the specificity of the method.

      • Pesticide residues
      • Chemical contaminants
  5. Development of Amphiphilic Coumarin Derivatives as Membrane-Active Antimicrobial Agents with Potent In Vivo Efficacy against Gram-Positive Pathogenic Bacteria

    • ACS Infectious Diseases
    • Increases in drug-resistant pathogens are becoming a serious detriment to human health. To combat pathogen infections, a new series of amphiphilic coumarin derivatives were designed and synthesized as antimicrobial agents with membrane-targeting action. We herein report a lead compound, 25, that displayed potent antibacterial activity against Gram-positive bacteria, including MRSA.

      • Staphylococcus aureus
      • Heavy Metals
      • Bacterial pathogens
      • Chemical contaminants
  6. High-Throughput Identification of Allergens in a Food System via Hybridization Probe Cluster-Targeted Next-Generation Sequencing

    • Journal of Agricultural and Food Chemistry
    • Food allergies (FAs) are a crucial public health problem and a severe food safety issue, resulting in an urgent need for an accurate method to detect all of the hidden allergens that exist in food systems. Current methods for detecting allergens typically utilize ELISA, PCR, or LC-MS, which are suitable for the confirmatory analysis of allergens from ingredients rather than unintended contaminants.

  7. Microplastics Contamination in Commercial Green Mussels from Selected Wet Markets in Thailand

    • Archives of Environmental Contamination and Toxicology
    • Mussels have been identified as sentinel organisms (around the world) that indicate microplastic (MP) pollution. Since they are filter feeders, they easily uptake MPs. Mussels sold in commercial markets have been identified as an ideal way to directly quantify human exposure to MPs through seafood consumption. There are no studies reported on MP contamination of market-sold species in Thailand.

  8. Lead Desorption and Its Potential Bioavailability in Soil Used for Disposing Lead-Contaminated Pomelo Peel: Effects of Contact Time and Soil pH

    • Water, Air, & Soil Pollution
    • Pomelo peel has been reported as an efficient biosorbent for lead removal from wastewater treatment processes. The current work aimed to examine the amounts of lead desorption from the biosorbent waste in amended soil samples for up to 3 months (10% w/w). The desorption experiments were performed under two widely used techniques, single extraction and column leaching. Lead desorption was evaluated using two common eluents, which were 0.01-M Ca(NO3)2 and 0.04-M EDTA solutions.

      • Heavy Metals
      • Chemical contaminants
  9. A Four-Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotypes C and D

    • Toxins
    • Human botulism can be caused by botulinum neurotoxin (BoNT) serotypes A to G. Here, we present an antibody-based antitoxin composed of four human monoclonal antibodies (mAbs) against BoNT/C, BoNT/D, and their mosaic toxins. This work built on our success in generating protective mAbs to BoNT /A, B and E serotypes. We generated mAbs from human immune single-chain Fv (scFv) yeast-display libraries and isolated scFvs with high affinity for BoNT/C, BoNT/CD, BoNT/DC and BoNT/D serotypes.

      • Clostridium botulinum
      • Bacterial pathogens
  10. The Use of Botulinum Toxin A as an Adjunctive Therapy in the Management of Chronic Musculoskeletal Pain: A Systematic Review with Meta-Analysis

    • Toxins
    • Several studies have investigated the effect of botulinum toxin A (BoNT-A) for managing chronic musculoskeletal pain, bringing contrasting results to the forefront. Thus far, however, there has been no synthesis of evidence on the effect of BoNT-A as an adjunctive treatment within a multimodal approach.

      • Clostridium botulinum
      • Bacterial pathogens
  11. Ciguatoxin-Producing Dinoflagellate Gambierdiscus in the Beibu Gulf: First Report of Toxic Gambierdiscus in Chinese Waters

    • Toxins
    • Ciguatera poisoning is mainly caused by the consumption of reef fish that have accumulated ciguatoxins (CTXs) produced by the benthic dinoflagellates Gambierdiscus and Fukuyoa. China has a long history of problems with ciguatera, but research on ciguatera causative organisms is very limited, especially in the Beibu Gulf, where coral reefs have been degraded significantly and CTXs in reef fish have exceeded food safety guidelines. Here, five strains of Gambierdiscus spp.

      • Shellfish toxins
      • Natural toxins
  12. Selective Breeding for Disease-Resistant PRNP Variants to Manage Chronic Wasting Disease in Farmed Whitetail Deer

    • Genes
    • Chronic wasting disease (CWD) is a fatal transmissible spongiform encephalopathy (TSE) of cervids caused by a misfolded variant of the normal cellular prion protein, and it is closely related to sheep scrapie. Variations in a host’s prion gene, PRNP, and its primary protein structure dramatically affect susceptibility to specific prion disorders, and breeding for PRNP variants that prevent scrapie infection has led to steep declines in the disease in North American and European sheep.

  13. Comparison of Pharmaceutical Characteristics between Brand-Name Meropenem and Its Generics

    • Antibiotics
    • This study aimed to provide comparative information of pharmaceutical properties, including particle morphology and distribution uniformity, solubility, presence of residual solvent and insoluble particles, and antimicrobial activities, between brand-name meropenem (Mepem®, BNM) and its six generic products (GPs A-F) marketed in China. Particles of GP-A and -C in dry powder had similar diameters of BNM, while other GPs were larger.

  14. Competitive growth kinetics of Campylobacter jejuni, Escherichia coli O157:H7, and Listeria monocytogenes with enteric microflora in a small‐intestine model

    • Journal of Applied Microbiology
    • Journal of Applied Microbiology, Accepted Article. Abstract
      Aims
      The biological events occurring during human digestion help understand the mechanisms underlying the dose-response relationships of enteric bacterial pathogens. To better understand these events, we investigated the growth and reduction behavior of bacterial pathogens in an in vitro model simulating the environment of the small intestine.

      • Campylobacter
      • Escherichia coli O157:H7
      • Listeria monocytogenes
      • Bacterial pathogens
  15. Different Responses of Soil Bacterial Communities to Nitrogen Addition in Moss Crust

    • Frontiers in Microbiology
    • Bacterial communities in soil serve an important role in controlling terrestrial biogeochemical cycles and ecosystem processes. Increased nitrogen (N) deposition in Northwest China is generating quantifiable changes in many elements of the desert environment, but the impacts of N deposition, as well as seasonal variations, on soil bacterial community composition and structure are poorly understood.

      • Seasonal Produce
      • Produce Safety
  16. Comprehensive Analysis of Bacterial Community Structure and Diversity in Sichuan Dark Tea (Camellia sinensis)

    • Frontiers in Microbiology
    • Bacteria and fungi present during pile-fermentation of Sichuan dark tea play a key role in the development of its aesthetic properties, such as color, taste, and fragrance. In our previous study, high-throughput sequencing of dark tea during fermentation revealed Aspergillus was abundant, but scarce knowledge is available about bacterial communities during pile-fermentation. In this study, we rigorously explored bacterial diversity in Sichuan dark tea at each specific stage of piling.

      • Bacterial pathogens
  17. Comparative Genome Sequence Analysis of Actinobacillus pleuropneumoniae Serovar 8 Isolates From Norway, Denmark, and the United Kingdom Indicates Distinct Phylogenetic Lineages and Differences in Distribution of Antimicrobial Resistance Genes

    • Frontiers in Microbiology
    • Actinobacillus pleuropneumoniae is the etiological agent of porcine pleuropneumonia, a disease of major impact on pig health, welfare, and productivity globally. Serovar 8 (APP) is the predominant clinical serovar in Norway and the United Kingdom (UK), and has been isolated from clinical cases in Denmark. The primary objective of this study was to characterize the genetic variability of isolates of A. pleuropneumoniae APP8 in the Norwegian population.

  18. Bacterial evolution during human infection: Adapt and live or adapt and die

    • PLOS Pathogens
    • by Matthew J. Culyba, Daria Van Tyne

  19. The type 3 secretion system requires actin polymerization to open translocon pores

    • PLOS Pathogens
    • by Brian C. Russo, Jeffrey K. Duncan-Lowey, Poyin Chen, Marcia B. Goldberg Many bacterial pathogens require a type 3 secretion system (T3SS) to establish a niche. Host contact activates bacterial T3SS assembly of a translocon pore in the host plasma membrane. Following pore formation, the T3SS docks onto the translocon pore. Docking establishes a continuous passage that enables the translocation of virulence proteins, effectors, into the host cytosol.

      • Bacterial pathogens
      • Shigella
  20. Finding the Next Flint: The Need to Update the Blood Lead Reference Value

    • American Journal of Public Health
    • In 2012, the US Centers for Disease Control and Prevention (CDC) adopted a blood lead reference value of 5 micrograms per deciliter and recognized that there is no known healthbased threshold for effects in children. Previously, the agency had identified a “level of concern” implying that blood lead levels (BLLs) under 10 micrograms per deciliter were not associated with harm.

      • Heavy Metals
      • Chemical contaminants
  21. Evaluation of the efficacy of a novel Vibrio vulnificus vaccine based on antibacterial peptide inactivation in turbot, Scophthalmus maximus

    • Fish & Shellfish Immunology
    • Author(s): Qin-qin Gu, Guang-hua Wang, Ning-qiu Li, Dong-fang Hao, Hong-mei Liu, Chang-biao Wang, Yong-hua Hu, Min Zhang

      • Vibrio
      • Bacterial pathogens
  22. Evaluation of various microwave-assisted acid digestion procedures for the determination of major and heavy metal elements in municipal solid waste incineration fly ash

    • Journal of Cleaner Production
    • Author(s): Siyu Han, Tongyao Ju, Yuan Meng, Yufeng Du, Honglin Xiang, Aikelaimu Aihemaiti, Jianguo Jiang

  23. Chemical stabilization remediation for heavy metals in contaminated soils on the latest decade: Available stabilizing materials and associated evaluation methods-A critical review

    • Journal of Cleaner Production
    • Author(s): Da-Mao Xu, Rong-Bing Fu, Jun-Xian Wang, Yu-Xiang Shi, Xiao-Pin Guo

  24. Improvement Roles of Zinc Supplementation in Low dose Lead Induced Testicular Damage and Glycolytic Inhibition in Mice

    • Toxicology
    • Author(s): Zhaoyu Zhang, Jun Yu, Jie Xie, Duanya Liu, Yongsheng Fan, Haitao Ma, Chunhong Wang, Zhidan Hong

      • Heavy Metals
      • Chemical contaminants
  25. The effects of cadmium on the development of Drosophila and its transgenerational inheritance effect

    • Toxicology
    • Author(s): Yun Mu, Xiaoyu Hu, Pingping Yang, Liran Sun, Wei Gu, Min Zhang

      • Heavy Metals
      • Chemical contaminants